26P Body mass index and clinical outcomes in Egyptian women with breast cancer: A multi-institutional study

Clinicopathologic Features of Breast Cancer in Egypt—Contemporary Profile and Future Needs: A Systematic Review and Meta-Analysis

“…Overall, the studies were of acceptable methodological quality, where 18 studies 15 , 17 , 23 , 24 , 27 - 29 , 31 - 36 , 39 - 41 , 43 , 44 were scored good, four studies scored very good, 22 , 30 , 37 , 42 and four studies scored satisfactory. 16 , 25 , 26 , 38 Funnel plots were generated for the included studies in the analysis for the AJCC stages, where the visual assessment showed relatively symmetrical plots with no evidence of publication bias (Data Supplement [Appendix Figure 1]).…”

“…In total, 662 studies were retrieved by our search, where 42 full-text papers were assessed for eligibility. Of them, 26 studies 15 - 17 , 22 - 44 were eligible for the current review and meta-analysis, including 31,172 BC cases. Figure 1 depicts the PRISMA flow chart for the search strategy.…”

“…Three studies 30 , 32 , 37 presented data extracted from population-based cancer registries, while other three studies 22 , 28 , 42 were based on hospital-based cancer registries. Furthermore, 16 studies 16 , 17 , 24 - 26 , 31 , 33 - 36 , 38 - 41 , 43 , 44 had collected data retrospectively and three studies 23 , 27 , 29 were cross-sectional studies. The data represent BC cases presented during approximately 2 decades, from 1997 till 2015.…”

“…The data represent BC cases presented during approximately 2 decades, from 1997 till 2015. Eight studies 16 , 17 , 22 , 24 , 33 , 36 , 41 , 43 represented the capital (Cairo), while 11 15 , 23 , 27 , 30 - 32 , 35 , 37 - 39 , 42 and six studies 25 , 26 , 28 , 34 , 40 , 44 represented North and South Egypt, respectively; however, one study 29 presented patients with BC in the capital and North Egypt simultaneously. It is worth noting that different editions of the AJCC staging manual (4 th -7 th ) were used by most of the studies.…”

“…Among 15,067 patients with BC in 12 studies, 15 - 17 , 24 , 27 , 29 , 31 , 32 , 36 , 38 , 40 , 44 the estimated mean age was 50.46 years (95% CI, 48.7 to 52.1; I 2 , 99%; Figure 3 ). Moreover, patients who are older than 40 years at presentation comprised 80% among 11,208 patients (95% CI, 73 to 85; I 2 , 95%; Data Supplement [Appendix Figure 4]).…”