275 Does systolic function determine the prognosis of hospitalized patients due to worsening heart failure?

Goncalves, A.; Azevedo, Ana; Almeida, Rui; Mascarenhas, Joana; Patacho, Marta; Rocha-Gonçalves, Francisco; Bettencourt, Paulo

doi:10.1016/s1567-4215(06)80177-3

Cited by 2 publications

(6 citation statements)

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“…HF readmission is more typical of patients who are men with reduced ejection fraction than women [59]. Two of the retrospective studies which contained information on LVEF [39,49] indicated that the tendency for readmission was higher Table 7 Objectives, study population, setting, type of study, and study endpoints as reported in studies with similar rates between males and females. Studies reported by primary author in alphabetical order (Continued) in men as compared to women.…”

Section: Discussionmentioning

confidence: 98%

“…The authors' survival analysis showed an advantage for females with HF and reduced ejection fraction [49]. In a retrospective study, Goncalves et al [39] found that males with preserved and reduced left ventricular systolic function were more likely to die and/or be re-admitted within 6 months.…”

Section: Non-hf Cardiovascular Causes Of Readmissionmentioning

confidence: 97%

“…Twelve studies reported higher readmission or composite outcomes in men. Among these, 6 studies demonstrated higher all-cause readmission rates [27,29,30,40,53,58] (Table 5) and 4 studies reported higher hazard ratios for composite events [28,31,39,50] (Table 6). In a prospective study, Nieminen et al [53] reported men having higher rates of all-cause readmission at 1 year compared to a 3-month endpoint.…”

Section: Outcomes Reportedmentioning

confidence: 99%

“…There was some indication that whether women were alone, supported socially by a partner, or working could impact readmission rates. Niemminen [39] discussed that readmitted women were more often retired, living alone or in special accommodation.…”

Section: Non-hf Cardiovascular Causes Of Readmissionmentioning

confidence: 99%

“…Nieminen [39] described that women underwent significantly fewer invasive procedures. However, Chang [36] found no sex differences in the use of critical life-saving procedures such as renal replacement therapy, mechanical ventilation, defibrillation or cardiopulmonary resuscitation.…”

Section: Differences In Interventionsmentioning

confidence: 99%

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Readmission rates following heart failure: a scoping review of sex and gender based considerations

Hoang‐Kim

Parpia

Freitas

et al. 2020

BMC Cardiovasc Disord

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Background: Although hospital readmission for heart failure (HF) is an issue for both men and women, little is known about differences in readmission rates by sex. Consequently, strategies to optimize readmission reduction programs and care strategies for women and men remain unclear. Our study aims were: (1) to identify studies examining readmission rates according to sex, and (2) to provide a qualitative overview of possible considerations for the impact of sex or gender. Methods: We conducted a scoping review using the Arksey and O'Malley framework to include full text articles published between 2002 and 2017 drawn from multiple databases (MEDLINE, EMBASE), grey literature (i.e. National Technical information, Duck Duck Go), and expert consultation. Eligible articles included an index heart failure episode, readmission rates, and sex/gender-based analysis. Results: The search generated 5887 articles, of which 746 underwent full abstract text consideration for eligibility. Of 164 eligible articles, 34 studies addressed the primary outcome, 103 studies considered sex differences as a secondary outcome and 25 studies stratified data for sex. Good inter-rater agreement was reached: 83% title/ abstract; 88% full text; kappa: 0.69 (95%CI: 0.53-0.85). Twelve of 34 studies reported higher heart failure readmission rates for men and six studies reported higher heart failure readmission rates for women. Using non composite endpoints, five studies reported higher HF readmission rates for men compared to three studies reporting higher HF readmission rates for women. Overall, there was heterogeneity between studies when examined by sex, but one observation emerged that was related to the timing of readmissions. Readmission rates for men were higher when follow-up duration was longer than 1 year. Women were more likely to experience higher readmission rates than men when time to event was less than 1 year. Conclusions: Future studies should consider different time horizons in their designs and avoid the use of composite measures, such as readmission rates combined with mortality, which are highly skewed by sex. Cointerventions and targeted post-discharge approaches with attention to sex would be of benefit to the HF patient population.

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Section: Discussionmentioning

confidence: 98%

Section: Non-hf Cardiovascular Causes Of Readmissionmentioning

confidence: 97%