29.6 Treatment of full thickness cartilage defects of the knee with the Trufit: technique and first results

Proud osteochondral autograft versus synthetic plugs — Contact pressures with cyclical loading in a bovine knee model

“…Other proposed benefits of synthetic technology include strength to resisting crush injury with impact or pressure. Further, the grafts are porous and hydrophilic, allowing the graft to act like a sponge, imbibing blood, marrow, and progenitor cells, which promote vascularization with host bone and cartilage ingrowth [14,15]. Although osteochondral autograft is generally used in defects 1-4 cm [2], there are reports of treated defects up to 8 cm [2] (MEGA-OATS), with donor-site morbidity related to size of plug harvested.…”