The present work aims to map kaolin occurrences on the Kefalos peninsula, SW Kos Island, Greece, through the elaboration of ASTER satellite imagery. The island of Kos is located on the eastern edge of the South Aegean Active Volcanic Arc (SAAVA) and is characterised by its complex geologic structure. During Plio-Pleistocene, the voluminous eruption of the Kos Plateau Tuff was recorded on Kefalos; the largest quaternary eruption in the Mediterranean. Kaolin is the product of hydrothermal alteration of the Pliocene volcanic rocks with rhyolitic composition. Our study emphasises the usefulness of satellite imagery combined with the Mixture Tuned Matched Filtering (MTMF) technique to detect occurrences of industrial minerals, kaolin-group minerals in this case, either in terms of raw mineral exploitation or by mapping hydrothermal alteration.