2023
DOI: 10.1039/d3nr05458f
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2D-MoS2-supported copper peroxide nanodots with enhanced nanozyme activity: application in antibacterial activity

Archana Kumari,
Jagabandhu Sahoo,
Mrinmoy De

Abstract: Peroxidase-like nanozymes (POD) are the upcoming class of new-generation antibiotics efficient for broad-spectrum antibacterial action. The POD-like activity employs the generation of reactive oxygen species (ROS), which has been utilized...

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Cited by 11 publications
(2 citation statements)
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“…ELISA is another option for obtaining sensitive and specific diagnosis. However, its main solution, horseradish peroxidase (HRP), which is commonly used in traditional detection methods, not only is complex and expensive, but also its biological activity is easily affected by external conditions such as temperature and pH, 9–11 further limiting ELISA's application in resource-limited areas. Therefore, many studies have focused on synthesizing nanozymes that are easy to prepare and have high stability to replace natural enzymes.…”
Section: Introductionmentioning
confidence: 99%
“…ELISA is another option for obtaining sensitive and specific diagnosis. However, its main solution, horseradish peroxidase (HRP), which is commonly used in traditional detection methods, not only is complex and expensive, but also its biological activity is easily affected by external conditions such as temperature and pH, 9–11 further limiting ELISA's application in resource-limited areas. Therefore, many studies have focused on synthesizing nanozymes that are easy to prepare and have high stability to replace natural enzymes.…”
Section: Introductionmentioning
confidence: 99%
“…In addition, pH-dependent release could exert a pivotal role in local disease treatment. 17–20 Under external stimulation, pH responsive nanocomposites can undergo protonation/deprotonation or formation and rupture of chemical bonds, thus inducing structural changes, alterations in volume, and modifications in solubility of the composites. Consequently, the pH-responsive interaction alters between drugs and nanocomposites, resulting in drug release from pH-responsive vectors.…”
Section: Introductionmentioning
confidence: 99%