Robotic bin-picking is a common process in modern manufacturing, logistics, and warehousing that aims to pickup known or unknown objects with random poses out of a bin by using a robot-camera system. Rapid and accurate object pose estimation pipelines have become an escalating issue for robot picking in recent years. In this paper, a fast 6-DoF (degrees of freedom) pose estimation pipeline for random bin-picking is proposed in which the pipeline is capable of recognizing different types of objects in various cluttered scenarios and uses an adaptive threshold segment strategy to accelerate estimation and matching for the robot picking task. Particularly, our proposed method can be effectively trained with fewer samples by introducing the geometric properties of objects such as contour, normal distribution, and curvature. An experimental setup is designed with a Kinova 6-Dof robot and an Ensenso industrial 3D camera for evaluating our proposed methods with respect to four different objects. The results indicate that our proposed method achieves a 91.25% average success rate and a 0.265s average estimation time, which sufficiently demonstrates that our approach provides competitive results for fast objects pose estimation and can be applied to robotic random bin-picking tasks. INDEX TERMS Robotic bin-picking, learning-based pose estimation, adaptive threshold, point pair features, multilayer segmentation, 3D sensing.