2D-Page Analysis of Vietnamese Colorectal Cancer Tissue Samples

Le, Kien; Vo, Phuong Uyen; Le, Kieu Minh; Pham, Hien Thi Thu; Nguyen, Huu Hung; Giap, Dang; Tran, Minh; Chau, Ngoc Phuc; Nguyen, Thi Dieu Hien

doi:10.1007/978-981-10-4361-1_48

6th International Conference on the Development of Biomedical Engineering in Vietnam (BME6)

2017

DOI: 10.1007/978-981-10-4361-1_48

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2D-Page Analysis of Vietnamese Colorectal Cancer Tissue Samples

Kien Le

Phuong Uyen Vo

Kieu Minh Le

et al.

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Molecular Pathways, Targeted Therapies, and Proteomic Investigations of Colorectal Cancer

Yerlikaya¹,

Zeren²

2023

CMM

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According to the GLOBOCAN 2020 data, colorectal cancer is the third most commonly diagnosed cancer and the second leading cause of cancer-related death. The risk factors for colorectal cancer include a diet abundant with fat, refined carbohydrates, animal protein, low fiber content, alcoholism, obesity, long-term cigarette smoking, low physical inactivity, and aging. Colorectal carcinomas are classified as adenocarcinoma, neuroendocrine, squamous cell, adenosquamous, spindle cell, and undifferentiated carcinomas. In addition, many variants of colorectal carcinomas are recently distinguished based on histological, immunological, and molecular characteristics. Recently developed targeted molecules in conjunction with standard chemotherapeutics or immune checkpoint inhibitors provide promising treatment protocols for colorectal cancer. However, the benefit of targeted therapies is strictly dependent on the mutational status of signaling molecules (e.g., KRAS) or mismatch repair systems. Here it is aimed to provide a comprehensive view of colorectal cancer types, molecular pathways-associated, recently developed targeted therapies as well as proteomic investigations applied to colorectal cancer for the discovery of novel biomarkers as well as new targets for treatment protocols.

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Molecular Pathways, Targeted Therapies, and Proteomic Investigations of Colorectal Cancer

Yerlikaya¹,

Zeren²

2023

CMM

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show abstract

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2D-Page Analysis of Vietnamese Colorectal Cancer Tissue Samples

Cited by 1 publication

References 2 publications

Molecular Pathways, Targeted Therapies, and Proteomic Investigations of Colorectal Cancer

Molecular Pathways, Targeted Therapies, and Proteomic Investigations of Colorectal Cancer

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