2D Shear Wave Elastography for Liver Fibrosis Evaluation

Popescu, Alina; Şirli, Roxana; Sporea, Ioan

doi:10.5772/intechopen.88183

Cited by 3 publications

(4 citation statements)

References 52 publications

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“…These studies have variable findings on the accuracy of SWE; however, its specificity and sensitivity are comparable to liver biopsy. Another study also found out that shear wave elastography is a reliable noninvasive modality for assessing liver elasticity (Popescu et al, 2019). In a study conducted on HBV patients for assessing the diagnostic value of SWE and liver biopsy, mean liver stiffness in F1, F2, F3, and F4 stage was 6.70 ± 2.65 kPa, 7.34 ± 3.84 kPa, 8.82 ± 3.24 kPa and 12.88 ± 5.25 kPa respectively (Kim and El-Serag, 2019), this was inline with the results of our study.…”

Section: Resultsmentioning

confidence: 94%

Comparison of Diagnostic Value of Shear Wave Elastography and Liver Biopsy in Assessing Liver Fibrosis

ZAHRA¹,

ZAFAR

Khalid

et al. 2022

Biol Clin Sci Res J

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This prospective study was designed to compare the specificity and sensitivity ofshear wave elastography(SWE) and liver biopsy in liver fibrosis staging. The study was conducted at Bakhtawar Amin Trust Hospital Multan from July 2021 to July 2022. The study was conducted on 90 patients who underwent liver biopsy due to pathologies, including congenital liver diseases or as possible liver donors. An experienced radiologist performs shear wave elastography. An experienced histopathologist assessed biopsy specimens. The mean age of the patients was 30 years. Out of 90 patients, 16 (17.7%) had Hep B or C, 20 (22.2%) were liver donors, and 54 (60%) had other liver diseases. Elastography results showed mean liver stiffness in F0–F1, F2, F3, and F4 stage fibrosis to 5.48 ± .52 kPa, 8.22 ± .42 kPa, 9.56 ± .32 kPa, and 12.41 ± 2.9kPa, respectively. Results of liver biopsy and SWE were significantly correlated (p=.0001).Shear wave elastography is an effective tool for the assessment of liver fibrosis.

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Section: Resultsmentioning

confidence: 94%

Comparison of Diagnostic Value of Shear Wave Elastography and Liver Biopsy in Assessing Liver Fibrosis

ZAHRA¹,

ZAFAR

Khalid

et al. 2022

Biol Clin Sci Res J

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“…Can be easily executed on modified commercial US devices (if the machine is provided with adequate software) [6,14] Offers the possibility of choosing a large and adjustable ROI in real-time [14,17,20] Good applicability: practicable among patients with ascites and obesity [6,20] Excellent diagnostic accuracy for advanced fibrosis and cirrhosis [6,20] Affected by acute hepatitis, food intake, liver congestion, cholestasis, and alcohol consumption [6] Table 1. Advantages and disadvantages of noninvasive elastographic techniques.…”

Section: D-shear Wave Elastography (2d-sw)mentioning

confidence: 99%

“…This technique has the advantage of displaying a real-time color-coded map overlayed on a B-mode image. Furthermore, 2D-SWE estimates LS expressed in kPa or m/s [20,77]. It should be executed in a well-visualized area of the right hepatic lobe, clear of large vessels, ligaments, gallbladder, and the liver capsule, with the patient situated in a supine position with breathing suspension [15].…”

Section: Appraisal Of Liver Fibrosis By 2d Shear Wave Elastography In...mentioning

confidence: 99%

Noninvasive Assessment of HCV Patients Using Ultrasound Elastography

Lupșor-Platon¹,

Şerban²,

Silion³

2022

Elastography - Applications in Clinical Medicine

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Among patients with chronic hepatitis C (CHC) infection, extensive research showed that fibrosis progression is a proper surrogate marker for advanced liver disease, eventually leading to dramatic endpoints such as cirrhosis and hepatocellular carcinoma. Therefore, there is growing interest in the use of noninvasive methods for fibrosis assessment in order to replace liver biopsy (LB) in clinical practice and provide optimal risk stratification. Elastographic techniques, such as Vibration Controlled Transient Elastography (VCTE), point-shear wave elastography (p-SWE), and 2D-SWE have shown promising results in this regard, with excellent performance in diagnosing hepatic cirrhosis, and great accuracy for steatosis detection through the Controlled Attenuation Parameter embedded on the VCTE device. In addition, the recent introduction of highly efficient direct-acting antivirals (DAAs) led to viral eradication and a significant decrease in liver damage, lowering the risk of hepatic decompensation, and HCC. Therefore, CHC patients need proper noninvasive and repeatable methods for adequate surveillance, even after treatment, as there still remains a risk of portal hypertension and HCC. However, the usefulness for monitoring fibrosis after the sustained virological response (SVR) needs further research.

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“…Therefore, 2D SWE is a reliable and current research method in modern radiology [12]. Number of publications and guidelines published in recent years indicates dynamics of this research Non-invasive diagnostics are safer and more acceptable to the patient, their use is increasing and the number of biopsies has been drastically reduced in some countries, especially for the routine evaluation of hepatitis B and C [8,13]. European Federation for societies for ultrasound in Medicine and Biology recommended the SWE that the last one assess the degree of liver stiffness in patients with CLD secondary to hepatitis especially hepatitis C [11].…”

Section: Introduction Introductionmentioning

confidence: 99%

Capacity of shear wave telephotography in the diagnosis of diffuse liver disease

2023

bmms

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Liver fi brosis is a process that is developed by a result of chronic liver disease progression,andifthisprocessisnotstopped,cirrhosisorhepatocellularcarcinomaprogression, and if this process is not stopped, cirrhosis or hepatocellular carcinoma (HCC)develops.Fibrousandcirrhoticchangesinthelivercausedamagetothestructure(HCC) develops. Fibrous and cirrhotic changes in the liver cause damage to the structure oftheliver,disruptionoffunction,andcomplicationsthatendangerhumanlifeandof the liver, disruption of function, and complications that endanger human life and leadtoafairlyhighpercentageoflethality.Thisiswhythediagnosisofdiffuseliverlead to a fairly high percentage of lethality.This is why the diagnosis of diffuse liver diseaseatanearlystageisafundamentalissueinmodernradiology.Modernimagingdisease at an early stage is a fundamental issue in modern radiology. Modern imaging techniqueswhicharenewlyintroducedinpractice,ultrasoundtelephotographyisusedtechniques which are newly introduced in practice, ultrasound telephotography is used todiagnoseliverfibrosis.Basedonthismethoditispossibletodetectthealteredto diagnose liver fi brosis. Based on this method it is possible to detect the altered elasticityoflivertissueinanon-invasivewayandtodeterminethedegreeoffibrosis.elasticity of liver tissue in a non-invasive way and to determine the degree of fi brosis. Earlydiagnosisofthediseaseanditstimelytreatmentleadtoabetterprognosis.TheEarly diagnosis of the disease and its timely treatment lead to a better prognosis. The aimoftheliteraturereviewistopresentthecapabilitiesofshearwavetelephotog-aim of the literature review is to present the capabilities of shear wave telephotog-raphyindiagnosingandevaluatingliverfibrosis.Wehaveresearchedandreviewedraphy in diagnosing and evaluating liver fi brosis. We have researched and reviewed therelevantscientificliterature,andbrieflysummarizedexistingknowledgeonthethe relevant scientifi c literature, and briefl y summarized existing knowledge on the resultsoftwo-dimensionalshearwaveelastographicstudyinhepatology.Theresultsresults of two-dimensional shear wave elastographic study in hepatology. The results ofthestudyrevealedtheundoubtedadvantagesandhighreliabilityofshearwaveof the study revealed the undoubted advantages and high reliability of shear wave telephotography,aswellasshoweditslimitations.Ourliteraturereviewconfirmsantelephotography, as well as showed its limitations. Our literature review confi rms an importantroleofshearwavetelephotographyinthediagnosisofdiffuseliverdiseasesimportant role of shear wave telephotography in the diagnosis of diffuse liver diseases andoutlinesaspectsoffutureresearchtofurtherimprovethisdiagnosticmethod.and outlines aspects of future research to further improve this diagnostic method.

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2D Shear Wave Elastography for Liver Fibrosis Evaluation

Cited by 3 publications

References 52 publications

Comparison of Diagnostic Value of Shear Wave Elastography and Liver Biopsy in Assessing Liver Fibrosis

Comparison of Diagnostic Value of Shear Wave Elastography and Liver Biopsy in Assessing Liver Fibrosis

Noninvasive Assessment of HCV Patients Using Ultrasound Elastography

Capacity of shear wave telephotography in the diagnosis of diffuse liver disease

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