2α-Hydroxytestosterone diacetate

Weeks, Charles M.; Duax, William L.; Osawa, Y.

doi:10.1107/s0567740875005559

Cited by 8 publications

(1 citation statement)

References 5 publications

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“…(iii) Despite the fact that combinations of C-H•••O interactions are involved in the arrangement of supramolecular assemblies, their contributions compared to the dispersion effects is small (see Table 2 for crystal lattice energies and Table S4, Supplementary Materials, for pairwise intermolecular energies). (iv) Hydrogen•••carbonyl distances implied in C-H•••O hydrogen bonding revealed similar values to those found in other analogues from the steroid group [18][19][20][21]. (v) From a conformational standpoint of steroid rings, the six-membered A rings are found to have an intermediate sofa-half-chair geometry; both the B and C rings were found to have a chair geometry; the five-membered D rings were found to have an envelope geometry.…”

Section: Nund (Nandrolone Undecanoate)supporting

confidence: 80%

Crystal Structure and Intermolecular Energy for Some Nandrolone Esters

Mare,

Muresan-Pop,

Purcea Lopes

et al. 2023

Molecules

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Nandrolone (Estr-4-en-17β-ol-3-one) is a derivative of testosterone and a naturally occurring anabolic–androgenic agent which belongs to the steroid group. Crystal structures of four short, medium and long esterified forms of nandrolone, including propionate, phenylpropionate, cypionate and undecanoate were determined using single-crystal X-ray diffraction. Crystal packing, supramolecular features and intermolecular interactions were described based on a quantitative and qualitative Hirshfeld surfaces analysis accompanied by evaluation of crystal energies and intermolecular interactions computation. Also, the solubility of the esters was investigated from a pharmaceutical perspective.

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Section: Nund (Nandrolone Undecanoate)supporting

confidence: 80%