[3 + 2] cycloaddition between cyclic diaryl λ³-bromanes and nitrones towards the formation of dihydrobenzisoxazoles and an evaluation of regioisomeric bioactivity

Abstract

Here the example of the efficient construction of important dihydrobenzisoxazole cores from the cycloaddition reactions between cyclic diaryl λ3-bromanes as the aryne precursors and nitrones is reported. Many dihydrobenzisoxazole-containing compounds...