3-(4-Chlorophenyl)-4-(4-methoxyphenyl)-6-(phenylselenylmethyl)-2,3,3a,3b,4,5,5a,6,1′′,2′′,3′′,4′′-dodecahydroazeto[2′,3′:3,4]pyrrolo[1,2-b]isoxazole-2-spiro-2′′-naphthalene-5,1′′-dione

Abstract

In the title compound, C36H31ClN2O4Se, the four-membered β-lactam ring is fused to a pyrrolidine ring. The central five-membered ring of the fused tricyclic system exhibits an envelope conformation with the N atom as the flap, while the other five-membered ring exhibits a twist conformation. The chloro­phenyl ring is almost perpendicular to the pyrrolidine ring, making a dihedral angle of 73.45 (1)°. The crystal structure is stabilized by weak inter­molecular C—H⋯O inter­actions and the packing is further enhanced by C—H ⋯N inter­actions and π–π inter­actions between benzene rings of tetra­lone groups in mol­ecules related by an inversion center, with a centroid–centroid separation of 3.8923 (2) Å.

Methyl 3-(4-bromophenyl)-2-(1H-indol-3-ylmethyl)-5-[1-(4-methoxyphenyl)-4-oxo-2-phenylazetidin-2-yl]-4-nitropyrrolidine-2-carboxylate

“…The bond lengths and angles in I are agree with those observed in a similar structure (Sundari Bhaskaran et al, 2006;Kamala et al, 2008). The β-lactam ring is planar with its internal angles in the range 84.4 (2) to 95.5 (2)°.…”

Methyl 3-(2-chlorophenyl)-2-(1H-indol-3-ylmethyl)-5-[1-(4-methoxyphenyl)-4-oxo-3-phenylazetidin-2-yl]-4-nitropyrrolidine-2-carboxylate

“…1) the four-membered β-lactam ring A (N4/C14-C16) is nearly planar, with a maximum deviation of 0.038 (4) Å for atom N1. The C14-C15 [1.581 (4) Å] and C15-C16 [1.523 (5) Å] bonds agree with those observed in similar structures (Bhaskaran et al, 2006;Kamala et al, 2008). The C14-C15-C16 [84.6 (2)°] bond angle is comparable to the corresponding value [87.0 (3)°)] in a related structure (Ülkü et al, 1997).…”

“…For general background, see: Bruggink (2001); Morin & Gorman (1982); Katritzky et al (1996); Georg (1993); Coyne et al (2007); Dobrowolski et al (2004); Cha et al (2006). For related literature, see: Bhaskaran et al (2006); Kamala et al (2008); Ü lkü et al (1997). For ring puckering parameters, see: Cremer & Pople (1975).…”