3,4-(Methylenedioxy)aniline as precursor to the synthesis of thiazolidin-4-ones

Masteloto, Hellen G.; Drawanz, Bruna Bento; Berwaldt, Gabriele A.; Neuenfeldt, Patrícia D.; Siqueira, Geonir M.; Cúnico, Wilson

doi:10.1007/s00706-014-1338-y

Cited by 4 publications

(1 citation statement)

References 31 publications

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“…In 2014, Masteloto et al [72] synthesized new 2‐aryl‐3‐(benzo[d][1,3]dioxol‐5‐yl)thiazolidin‐4‐ones 181 by one‐pot reaction of amine 179 , cyclohexanone 44 , and thioglycolic acid 3 in quantitative yields (Scheme 41).…”

Section: Synthesis Of Spirothiazolidin‐4‐onesmentioning

confidence: 99%

A review on advances in synthetic methodology and biological profile of spirothiazolidin‐4‐ones

Yadav

Chaudhary

2022

Journal of Heterocyclic Chem

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Heterocycles are important structural components in pharmacophores that are currently being used to treat several diseases. Among the various heterocyclic scaffolds, nitrogen and sulfur containing spiroheterocycles are essential structural motifs that constitute diverse biodynamic agents. In the last two decades, a paradigm shift has occurred in the synthesis of spirothiazolidin-4-ones by replacing conventional and multi-step synthesis with green protocols, that use novel organo and nanocatalysts. In this review, literature on spirothiazolidin-4-ones from years 2000-2021 has been summarized into groups of different synthetic strategies and their potential biological activities.

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Section: Synthesis Of Spirothiazolidin‐4‐onesmentioning

confidence: 99%

A review on advances in synthetic methodology and biological profile of spirothiazolidin‐4‐ones

Yadav

Chaudhary

2022

Journal of Heterocyclic Chem

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ChemInform Abstract: 3,4‐(Methylenedioxy)aniline as Precursor to the Synthesis of Thiazolidin‐4‐ones (IV).

et al. 2015

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3,4-(Methylenedioxy)aniline as Precursor to the Synthesis of Thiazolidin-4-ones (IV). -These referred heterocycles (IV) are potent biologically active compounds due to the presence of two important moieties, thiazolidinone and 1,3-benzodioxole. -(MASTELOTO, H. G.; DRAWANZ, B. B.; BERWALDT, G. A.; NEUENFELDT, P. D.; SIQUEIRA, G. M.; CUNICO*, W.; Monatsh. Chem. 146 (2015) 2, 327-334, http://dx.doi.org/10.1007/s00706-014-1338-y ; Lab. Quim. Apl. Bioativos, Univ. Fed. Pelotas, 96010 Pelotas, RS, Brazil; Eng.) -A. Forchert 30-183

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Thiazolidin-4-ones from 4-(methylthio)benzaldehyde and 4-(methylsulfonyl)benzaldehyde: Synthesis, antiglioma activity and cytotoxicity

Silva

Soares

et al. 2016

European Journal of Medicinal Chemistry

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3,4-(Methylenedioxy)aniline as precursor to the synthesis of thiazolidin-4-ones

Cited by 4 publications

References 31 publications

A review on advances in synthetic methodology and biological profile of spirothiazolidin‐4‐ones

A review on advances in synthetic methodology and biological profile of spirothiazolidin‐4‐ones

ChemInform Abstract: 3,4‐(Methylenedioxy)aniline as Precursor to the Synthesis of Thiazolidin‐4‐ones (IV).

Thiazolidin-4-ones from 4-(methylthio)benzaldehyde and 4-(methylsulfonyl)benzaldehyde: Synthesis, antiglioma activity and cytotoxicity

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