2004
DOI: 10.1023/b:rujo.0000034950.28394.e0
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3-Azabicyclo[3.3.1]nonane Derivatives: IX. Synthesis and Molecular Structure of 3-Azabicyclo[3.3.1]nonane-1,5-diamines in Solution and in Solid State

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Cited by 4 publications
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“…The presence of two nitro groups in a molecule of potential biologically active compound could give rise to increased toxicity [4]. 1,5-Dinitro-3-azabicyclo[3.3.1]non-6-enes were previously reduced with molecular hydrogen over nickel or carbon-supported palladium to obtain the corresponding saturated diamines [5] or mixtures of saturated and unsaturated diamines [6]. Taking the above into account, in the present work we made an attempt to find conditions for selective preparation of unsaturated diamines of the 3-azabicyclo[3.3.1]nonane series.…”
mentioning
confidence: 99%
“…The presence of two nitro groups in a molecule of potential biologically active compound could give rise to increased toxicity [4]. 1,5-Dinitro-3-azabicyclo[3.3.1]non-6-enes were previously reduced with molecular hydrogen over nickel or carbon-supported palladium to obtain the corresponding saturated diamines [5] or mixtures of saturated and unsaturated diamines [6]. Taking the above into account, in the present work we made an attempt to find conditions for selective preparation of unsaturated diamines of the 3-azabicyclo[3.3.1]nonane series.…”
mentioning
confidence: 99%