3‐Azabicyclo[3.3.1]nonane Derivatives. Part 6. Synthesis of Heterocyclic Analogues of γ‐Aminobutyric Acid from 3,5‐Dinitrobenzoic Acid.

Abstract

Multi-membered N-heterocyclesR 0690 3-Azabicyclo[3.3.1]nonane Derivatives. Part 6. Synthesis of Heterocyclic Analogues of γ-Aminobutyric Acid from 3,5-Dinitrobenzoic Acid. -The synthesis of a series of 7-carboxy-1,5-dinitro-3-azabicyclononenes [cf. (IV), (VI)], potential intermediates in the preparation of heterocyclic analogues of γ-aminobutyric acids, by reduction of 3,5-dinitrobenzoic acid (I) and subsequent Mannich reactions is reported. -(SHAHKEL'DYAN, I. V.; MELEKHINA, E. K.; ATROSHCHENKO, Y. M.; EFREMOV, Y. A.; ALIFANOVA, E. N.; KOPYSHEV, M. V.; TROITSKII, N. A.; SUBBOTIN, V. A.; NIKISHINA, M. B.; Russ.