3. Evaluation of the antimycotic activity of grape fruit plant extract on candida species-an invitro study

Prasad, Anupama

doi:10.4103/0972-4052.246639

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It showed positive inhibition zones assay results, suggesting good antifungal activity against C. albicans [56, 57] (Table 2). Prasad and colleagues investigated the effect of a grapefruit leaf extract against Candida species [58]. The results showed that this EO extract was more active on C. albicans and C. krusei than the commercially available Amphotericin B [58] (Table 2).…”

Section: Natural Compounds With Anti-candida Activitiesmentioning

confidence: 99%

See 1 more Smart Citation

Natural Compounds with Antimicrobial Activities in Oral Candida Infections during Head and Neck Radiotherapy

Imperia,

Bonincontro,

Altomare

et al. 2023

Chemotherapy

View full text Add to dashboard Cite

Backgrounds: Oral colonization and infections are frequently observed in patients during and soon after radiation therapy (RT). Infective mucositis is a common side effect associated with cancer therapy, characterized by an inflammation of the oral mucous membranes with histological mucosal and submucosal changes. Ulcerative mucositis is responsible for significant pain, impairing the patient's nutritional intake and leading to local or systemic infections promoting mycosis due to several species of the genus Candida. According to international guidelines, treatment of candidiasis depends on the infection site and patient’s condition. Summary: Recently several studies have shown the protective role of natural compounds counteracting the activity of Candida biofilms. The aim of this review is to discuss the antimicrobial activities of natural compounds in fungal infections, especially Candida spp., during and soon after radiotherapy. Indeed new molecules are being discovered and assessed for their capacity to control Candida spp. growth and, probably in the future, will be used to treat oral candidiasis, overall, during radiotherapy. This review reports several preliminary data about preclinical and clinical evidence of their efficacy in the prevention and/or treatment of mucositis due to Radiotherapy with a brief description of the natural compounds with anti-Candida activities. Key messages: The increase in the resistance to the available antifungal drugs related to Candida spp. infections increased as well as drug interactions, urging the development of innovative and more effective agents with antifungal action. Recent preclinical and clinical studies are identifying natural substances with anti-inflammatory and antifungal activity that could be tested in the prevention of candidiasis in patients undergoing radiotherapy. Further studies are needed to confirm these preliminary data.

show abstract

Section: Natural Compounds With Anti-candida Activitiesmentioning

confidence: 99%

“…Prasad and colleagues investigated the effect of a grapefruit leaf extract against Candida species [58]. The results showed that this EO extract was more active on C. albicans and C. krusei than the commercially available Amphotericin B [58] (Table 2).…”

Section: Natural Compounds With Anti-candida Activitiesmentioning

confidence: 99%