3-Farnesylindole from Uvaria pandensis verdc.

(R)-3-(8'-Hydroxyfarnesyl)-indole and other chemical constituents from the flowers of Anomianthus dulcis and their antimalarial and cytotoxic activities

“…The dried flowers of A. dulcis were extracted with methanol and the crude extract was separated using various chromatographic techniques which led to the isolation of a new indole alkaloid, (R)-3-(8'-hydroxyfarnesyl)-indole (1), and nine known compounds; 3farnesylindole (2) (Nkunya et al 1987), (±)-pinostrobin 3 The UV spectrum showed maximum absorption bands at λmax 222 and 283 nm which corresponded to an indole derivative (Sangster et al 1964). The IR spectrum showed stretching bands for a hydroxy group at 3415 cm -1 and an alkene C=C at 1617 cm -1 .…”

Oridamycins A and B, Anti-Saprolegnia parasitica Indolosesquiterpenes Isolated from Streptomyces sp. KS84

“…Several indolosesquiterpenes such as polyalthenol, suaveolindole, greenwayodendrine, polyavolinamide, polyveoline, and 3-farnesylindole derivatives , have been reported from plants. Until recently, no indolosesquiterpenes had been isolated from bacteria, although indoloditerpenes, such as paspalicine, paxilline, janthitrems, lolitrems, and penitrems, have been isolated from fungi.…”

Recent progress in the chemistry of indole alkaloids and mould metabolites

“…In the first synthesis20 of (+)-cis-trikentrin A (lo), one of a group of biologically active indoles isolated from the sponge TrikentrionJZhbellijiorme, 21 the cyclopentane ring is formed by a radical cyclization on the bromoalcohol (1 l), prepared by a Grignard reaction on o-bromoacetophenone. Subsequent stages to the azidoester (12) are conventional, and the indole ring is then formed by Moody's method (Scheme 3).…”