3-Mercapto-1,2,4-triazole Functionalized Fe₃O₄ Based Cu Nanoparticles: A Capable Catalyst for the Synthesis of Diverse Tetrazoles from Amino Acids

A Mesoporous Magnetic Fe3O4/BioMOF-13 with a Core/Shell Nanostructure for Targeted Delivery of Doxorubicin to Breast Cancer Cells

“…Tight covalent bonding between the oxygen atoms (located on the surface of the magnetic particles) and the silicon atoms in the CPTMS structure leads to well surface coating. 49 The main reason for choosing the CPTMS is to provide C−Cl groups onto the surfaces, which are appropriate chemical sites for further binding of the Ade from its free amine site (nucleophilic substitution). Moreover, the formed silica network on the surface of the Fe 3 O 4 NPs physically supports the magnetic core and enhances its structural stability.…”

“…Then, the surface of the particles was modified by 3-chloroporpyl trimethoxysilane (CPTMS). Tight covalent bonding between the oxygen atoms (located on the surface of the magnetic particles) and the silicon atoms in the CPTMS structure leads to well surface coating . The main reason for choosing the CPTMS is to provide C–Cl groups onto the surfaces, which are appropriate chemical sites for further binding of the Ade from its free amine site (nucleophilic substitution).…”

Nanomaterial catalyzed green synthesis of tetrazoles and its derivatives: a review on recent advancements

“…The prepared magnetic nano-catalyst was effectively utilized for synthesis of tetrazoles using several amino acids in aqueous medium at 40 C (entry 5, Table 6). 89 Similarly, in another alternative method, Fe 3 O 4 /SiO 2 /CPTMS/ AT/Cu nano catalyst was developed for tetrazole synthesis from triethyl orthoformate, sodium azide and amino acids in ethanol at reux condition (Table 6, entry 6). 90 A copper-based magnetic heterogeneous catalyst was prepared via functionalization surface of nano Fe 3 O 4 @SiO 2 with polyvinyl alcohol and the resultant Fe 3 O 4 @SiO 2 -PVA was then immobilized with copper(II) complex.…”

“…The prepared magnetic nano-catalyst was effectively utilized for synthesis of tetrazoles using several amino acids in aqueous medium at 40 °C (entry 5, Table 6 ). 89 Similarly, in another alternative method, Fe 3 O 4 /SiO 2 /CPTMS/AT/Cu nano catalyst was developed for tetrazole synthesis from triethyl orthoformate, sodium azide and amino acids in ethanol at reflux condition ( Table 6 , entry 6). 90 …”