3 Review of multiple sclerosis at the neurology clinic in Sarajevo during 2006

Alajbegovic, Azra; Suljić, Enra; Loga, Nataša; Alajbegović, Salem

doi:10.1017/s0924270800032841

Cited by 3 publications

(3 citation statements)

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“…Finally, 128 studies were included in the qualitative and quantitative synthesis (Supplementary Table 2). 12…”

Section: Resultsmentioning

confidence: 99%

Incidence and risk factors of post-stroke seizures and epilepsy: systematic review and meta-analysis

Nandan,

Zhou,

Demoe

et al. 2023

J Int Med Res

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Objective Due to variability in reports, the aim of this meta-analysis was to evaluate the incidence and risk factors of post-stroke early seizures (ES) and post-stroke epilepsy (PSE). Methods The MEDLINE, EMBASE and Web of Science databases were searched for post-stroke ES/PSE articles published on any date up to November 2020. Post-stroke ES included seizures occurring within 7 days of stroke, and PSE included at least one unprovoked seizure. Using random effects models, the incidence and risk factors of post-stroke ES and PSE were evaluated. The study was retrospectively registered with INPLASY (INPLASY2023100008). Results Of 128 included studies in total, the incidence of post-stroke ES was 0.07 (95% confidence interval [CI] 0.05, 0.10) and PSE was 0.10 (95% CI 0.08, 0.13). The rates were higher in children than adults. Risk factors for post-stroke ES included hemorrhagic stroke (odds ratio [OR] 2.14, 95% CI 1.44, 3.18), severe strokes (OR 2.68, 95% CI 1.73, 4.14), cortical involvement (OR 3.09, 95% CI 2.11, 4.51) and hemorrhagic transformation (OR 2.70, 95% CI 1.58, 4.60). Risk factors for PSE included severe strokes (OR 4.92, 95% CI 3.43, 7.06), cortical involvement (OR 3.20, 95% CI 2.13, 4.81), anterior circulation infarcts (OR 3.28, 95% CI 1.34, 8.03), hemorrhagic transformation (OR 2.81, 95% CI 1.25, 6.30) and post-stroke ES (OR 7.24, 95% CI 3.73, 14.06). Conclusion Understanding the risk factors of post-stroke ES/PSE may identify high-risk individuals who might benefit from prophylactic treatment.

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“…Finally, 128 studies were included in the qualitative and quantitative synthesis (Supplementary Table 2). 12…”

Section: Resultsmentioning

confidence: 99%

Incidence and risk factors of post-stroke seizures and epilepsy: systematic review and meta-analysis

Nandan,

Zhou,

Demoe

et al. 2023

J Int Med Res

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“…5 It is confirmed that atherosclerosis with higher intraocular pressure has a bad influence on pulse volume level in glaucoma. 6 So, we have done this study to evaluate the fasting lipid profile level in normotensive and non-diabetic glaucoma patients coming to our hospital in OPD of Ophthalmology department G.G.S. Medical College, Faridkot.…”

Section: Introductionmentioning

confidence: 99%

A comparative study of fasting serum lipid profile between glaucoma patients and controls

Dhawan¹,

Singh²,

Kamble³

2019

IJCEO

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Glaucoma constitutes 10% of blindness worldwide which is the third most common cause of blindness with majority of people being undiagnosed in developing countries. Aims: To assess and compare serum lipid profile between normotensive, non diabetic POAG patients and normotensive, non diabetic non glaucoma controls. Results: 1: Mean total cholesterol levels were (219±60.010) mg/dl and (191.26±43.167) mg/dl in glaucoma patients and controls respectively and the difference was statistically significant (p < 0.011); 2: Statistically significant difference (p < 0.019) was observed in mean LDL-C value in glaucoma patients (152.26±58.791) mg/dl and controls (125.70±44.976) mg/dl. Conclusion: Higher total cholesterol levels and LDL-C levels were found in glaucoma patients as compared to controls. While there was no significant difference of serum triglycerides, HDL-C, VLDL-C levels between both the groups.Exclusion Criteria 1. Patients with diabetes mellitus.

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“…Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterized by the deterioration of myelin and axons in various parts of the brain and spinal cord (1, 2). It more often affects women than men (ratio from 3:1 to 1.8:1).…”

Section: Introductionmentioning

confidence: 99%

Stress as Provoking Factor for the First and Repeated Multiple Sclerosis Seizures

Djelilovic-Vranic

Alajbegovic²,

Tirić–Čampara³

et al. 2012

Mater Sociomed

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Introduction:Multiple sclerosis is an inflammatory, autoimmune, disease of the white mass of the brain, which sometimes may involve the gray matter (subcortical and ones in the anterior horns of the spinal cord) with the chronic nature and generally with progressive course. As a possible cause of this disease state are listed genetic predisposition, early viral infections and environmental factors, with special effects of stress as a provoking factor in first episode of the disease and relapses because stress leads to modulation of the immune system and immune response to various causes.Goal:To determine the existence of intense stressful events as a factor in the development of the first episode of illness and worsening of the seizures.Material and methods:We analyzed all newly discovered cases of multiple sclerosis over a two year period (January 2010 – December 2011) during the first or second hospitalization, and worsening of seizures for previously diagnosed patients in this period. In order to confirm the MS diagnosis are taken history, neurological examination, MRI of the brain, VEP, CSF examination and for those with repeated hospitalization only follow-up of EDSS scores trough neurological examination.Results:During the two year period there were 109 newly diagnosed cases of MS from which 80 F and 29 M (ratio 2.7:1), aged 17-59 years, mean age 32.93±9.69 years and 41 patients (29 F and 12M with seizures worsening in previously diagnosed disease. Disease duration was from 6 months to 17 years. 72.94% had relapsing-remitting course of the disease (RRMS) and 27.1% had secondary progressive type (SPMS). Stress as a provoking factor preceded in 47.44% the first episode of the disease, infections (respiratory) in 18.3%, and the pregnancy with postpartum period in 8.77% women, whereas in the group of patients with previously diagnosed illness relapse (n=41) showed that the infection is most common precipitating factor which preceded relapse in 58.54% of patients, stress in 29.02%) and the pregnancy with postpartum period in 12.5% of patients.Conclusion:An intensive stressor is certainly one of the triggers for the development of Multiple Sclerosis, as the first episode and worsening of previously established disease.

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3 Review of multiple sclerosis at the neurology clinic in Sarajevo during 2006

Cited by 3 publications

References 0 publications

Incidence and risk factors of post-stroke seizures and epilepsy: systematic review and meta-analysis

Incidence and risk factors of post-stroke seizures and epilepsy: systematic review and meta-analysis

A comparative study of fasting serum lipid profile between glaucoma patients and controls

Stress as Provoking Factor for the First and Repeated Multiple Sclerosis Seizures

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