3-Year Clinical Outcome of Patients With Chronic Total Occlusion Treated With Drug-Eluting Stents

Felice, Francesco De; Fiorilli, Rosario; Parma, Antonio; Nazzaro, Marco Stefano; Musto, Carmine; Sbraga, Fernando; Caferri, Giorgia; Violini, Roberto

doi:10.1016/j.jcin.2009.09.013

Cited by 45 publications

(24 citation statements)

References 20 publications

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“…6). TLR and TVR were significantly lower in the DES group in three [7,24,31] of four studies and similar in one study with small sample size [28,29] (Fig. 7).…”

Section: Clinical Outcomes After >12 Monthssupporting

confidence: 66%

“…In instances where multiple analyses of CTO outcomes were reported from a single center (RapamycinEluting Stent Evaluated at Rotterdam Cardiology Hospital registry (RESEARCH) registry [20,[27][28][29], Ospedale S. Camillo Forlanini, Rome, Italy [23,30,31] and Friedrich-Schiller University Jena in Jena, Germany [21,32]), only one study from each center, describing the largest patient cohort and/or longest duration of follow-up was selected. SES or PES was utilized in all retrieved studies; no trials reporting outcomes after everolimus-eluting or zotarolimus-eluting stent implantation in CTOs were found.…”

Section: Study Selectionmentioning

confidence: 99%

“…Long-term outcomes (after >12 months) were reported in five studies (Table III), the two randomized trials (SCANDSTENT [26] and PRISON II [7]) and three nonrandomized studies [24,28,29,31]; however, SCANDSTENT only reported aggregate major cardiac adverse event rates (that were lower in the DES group [26]). …”

Section: Clinical Outcomes After >12 Monthsmentioning

confidence: 99%

See 2 more Smart Citations

Use of drug‐eluting stents for chronic total occlusions: A systematic review and meta‐analysis

Saeed

Kandzari

Agostoni

et al. 2011

Cathet Cardio Intervent

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“…6). TLR and TVR were significantly lower in the DES group in three [7,24,31] of four studies and similar in one study with small sample size [28,29] (Fig. 7).…”

Section: Clinical Outcomes After >12 Monthssupporting

confidence: 66%

Section: Study Selectionmentioning

confidence: 99%

See 1 more Smart Citation

Use of drug‐eluting stents for chronic total occlusions: A systematic review and meta‐analysis

Saeed

Kandzari

Agostoni

et al. 2011

Cathet Cardio Intervent

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“…This is the first report of SVG aneurysm successfully treated by catheter intervention including PCI for the CTO of native coronary artery and TCE for the SVG aneurysm. In case of an SVG aneurysm that remains patent, percutaneous revascularization of native coronary artery followed by TCE is considered a useful strategy to treat an SVG aneurysm because the introduction of drug‐eluting stent has resulted in improved patency of CTO in the chronic phase 14 and the initial success rate of PCI for CTO lesions has been improved with advancing of PCI techniques 15.…”

Section: Discussionmentioning

confidence: 99%

A case of giant saphenous vein graft aneurysm successfully treated with catheter intervention

Katoh

Nozue

Michishita

2015

Cathet Cardio Intervent

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The patient was a 67‐year‐old man who had undergone coronary artery bypass graft surgery using a saphenous vein graft (SVG) 22 years before. Computed tomography angiogram revealed a large aneurysm of the SVG (38 × 42 mm in diameter; 80‐mm long) and total occlusion of the left anterior descending artery (LAD). We first performed percutaneous coronary intervention for chronic total occlusion of the native LAD with bi‐directional approach via the SVG. One month later, we performed the trans‐catheter embolization of the SVG and occluded the SVG using multiple coils. This case demonstrates that trans‐catheter embolization after recanalization of native coronary artery is an effective strategy to treat an SVG aneurysm. © 2015 Wiley Periodicals, Inc.

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“…Accordingly, PCI for CTO has been more generally performed. In addition, drug-eluting stents (DESs) for treatment of CTO lesions has improved angiographic and clinical long-term outcomes [11][12][13]. However, even now, restenosis and reocclusion rate of PCI for CTO lesions has been high [14].…”

Section: Introductionmentioning

confidence: 99%

Neointimal Characteristics after Everolimus-Eluting Stents Implantation for Chronic Total Occlusion: An Optical Coherence Tomographic Study

Okamoto¹,

Yasumura²,

Yasumoto³

et al. 2017

Interv Cardiol J

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Objectives: We investigated neointimal characteristics after everolimus-eluting stent (EES) implantation in chronic total occlusion (CTO) using optical coherence tomography (OCT).Background: CTO is one of the major risk factors for restenosis and reocclusion even in drug-eluting stent era, but detailed neointimal characteristics after stent implantation in CTO is unclear. Methods:We divided our patients (35 EESs) into three groups: patients with stenting for non-CTO lesions (non-CTO group), patients with subintimal stenting (CTO subintima group) and with intra true-lumen stenting for CTO lesions (CTO true lumen group). We compared OCT parameters included the percentage of neointimal hyperplasia area obstruction (%NHAO), mean neointimal hyperplasia (NIH) thickness, the proportion of uncovered struts, the proportion of malapposed struts at cross sectional level and at strut level among three groups.Results: NIH and %NHAO were significantly lowest in CTO subintima group (5 EESs) and highest in CTO true-lumen group (4 EESs) (CTO subintima vs. CTO true-lumen vs. non- , respectively) while the proportions of uncovered struts and malapposed struts were significantly highest in CTO subintima group and significantly lowest in CTO true-lumen group among the three groups (CTO subintima vs. CTO true-lumen vs. non-CTO: 109 (18.7) vs. 47 (4.7) vs. 375 (7.9) and 36 (6.2) vs. 0 (0) vs. 45 (0.95), respectively). Conclusions:We revealed by OCT that stents implanted in subintima in CTO lesions may have more risks related to stent thrombosis such as malapposed struts and uncovered struts, while stents implanted in true lumen in CTO lesions may have thicker neointimal coverage that might have occurred restenosis.

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3-Year Clinical Outcome of Patients With Chronic Total Occlusion Treated With Drug-Eluting Stents

Abstract: After 3 years, DES were superior to BMS in reducing MACE in patients with CTO and should be considered the preferred treatment strategy.

Cited by 45 publications

References 20 publications

Use of drug‐eluting stents for chronic total occlusions: A systematic review and meta‐analysis

Use of drug‐eluting stents for chronic total occlusions: A systematic review and meta‐analysis

A case of giant saphenous vein graft aneurysm successfully treated with catheter intervention

Neointimal Characteristics after Everolimus-Eluting Stents Implantation for Chronic Total Occlusion: An Optical Coherence Tomographic Study

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