3 Year Immunological Follow Up of the First Bilateral Arm Transplant World Wide

Stangl, Manfred; Biemer, E; Nerlich, Andreas; Höhnke, C

doi:10.1097/00007890-201211271-00641

Cited by 3 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The composite recovery of extrinsic and intrinsic motor function as well as functional sensibility has allowed recipients to independently perform most activities of daily living, including eating, driving, grasping objects, riding a motorcycle or bicycle, using the telephone, and writing 40 . As expected, the more distal transplants have demonstrated relatively greater motor and sensory function as the nerves have to regenerate over shorter distances; however, good results have been obtained even with proximal-level amputations as high as the deltoid 61,62 . Despite these overall good results, detailed functional assessments involving comparisons with highly trained prosthetic users as well as comparisons based on the levels transplanted are necessary in order to truly narrow and refine the indications for hand transplantation.…”

Section: Functional Resultsmentioning

confidence: 53%

Hand Transplantation

et al. 2014

View full text Add to dashboard Cite

Section: Functional Resultsmentioning

confidence: 53%

Hand Transplantation

et al. 2014

View full text Add to dashboard Cite

“…To a degree, the level of transplant may determine how much motor and sensory function recovers after surgery, with better outcomes expected in more distal transplants. However, a limited number of above-elbow transplantations have been performed, with reasonable results [21,22].…”

Section: Discussionmentioning

confidence: 99%

Upper extremity transplantation: current concepts and challenges in an emerging field

Elliott¹,

Tintle

Levin

2013

Curr Rev Musculoskelet Med

View full text Add to dashboard Cite

Loss of an isolated upper limb is an emotionally and physically devastating event that results in significant impairment. Patients who lose both upper extremities experience profound disability that affects nearly every aspect of their lives. While prosthetics and surgery can eventually provide the single limb amputee with a suitable assisting hand, limited utility, minimal haptic feedback, weight, and discomfort are persistent problems with these techniques that contribute to high rates of prosthetic rejection. Moreover, despite ongoing advances in prosthetic technology, bilateral amputees continue to experience high levels of dependency, disability, and distress. Hand and upper extremity transplantation holds several advantages over prosthetic rehabilitation. The missing limb is replaced with one of similar skin color and size. Sensibility, voluntary motor control, and proprioception are restored to a greater degree, and afford better dexterity and function than prosthetics. The main shortcomings of transplantation include the hazards of immunosuppression, the complications of rejection and its treatment, and high cost. Hand and upper limb transplantation represents the most commonly performed surgery in the growing field of Vascularized Composite Allotransplantation (VCA). As upper limb transplantation and VCA have become more widespread, several important challenges and controversies have emerged. These include: refining indications for transplantation, optimizing immunosuppression, establishing reliable criteria for monitoring, diagnosing, and treating rejection, and standardizing outcome measures. This article will summarize the historical background of hand transplantation and review the current literature and concepts surrounding it.

show abstract

“…To a extent, the level of transplant may decide how much motor and sensory function improves after surgery, with enhanced results anticipated in more distal transplants. Nevertheless, a limited number of above-elbow transplantations have been done, with sensible outcomes [40] [41].…”

Section: The Inclusive Data From the International Registry On Hand Amentioning

confidence: 99%

The Relevant Roles of Plastic and Orthopedic Surgery in Hand Salvage

Almutlaq¹,

Al‐Qattan²,

Alturkstani³

et al. 2018

MPS

View full text Add to dashboard Cite

Over the recent past few years, there is a huge innovation in plastic surgery and orthopedic surgery through implantation of new techniques, which enabled a great level of success in hand salvage. Conditions such as trauma, tumor, sepsis, or vascular disease, may necessitate hand salvage. The most frequent argument among surgeon from different subspecialties (orthopedics, plastics, trauma, and vascular surgery) are characterized by in what way each one can do his own part of the salvage operation, be it bony fixation, revascularization, or soft-tissue coverage, but none of them is sure whether it should be endeavored. What is necessary in such clinical situations is an interdisciplinary team attitude led by individual or groups of clinicians who are conversant not only with their identifiable subspecialized skills but also with those of their coworkers and the consequences accompanying the joined efforts at hand salvage. The perception of orthoplastic surgery is based on such an indication, where the integrated skills and techniques of the orthopedic surgeon and reconstructive microsurgeon are performed in recital to direct efforts concerning hand salvage or choose against it when it is not designated. The current article reviews the roles of orthopedic and plastic surgery and how this team can deal with the existing techniques to improve outcomes in hand salvage surgery.

show abstract

3 Year Immunological Follow Up of the First Bilateral Arm Transplant World Wide

Cited by 3 publications

References 0 publications

Hand Transplantation

Hand Transplantation

Upper extremity transplantation: current concepts and challenges in an emerging field

The Relevant Roles of Plastic and Orthopedic Surgery in Hand Salvage

Contact Info

Product

Resources

About