30-day all-cause readmission rates among a cohort of individuals with rare conditions

Bennett, Kevin J.; Mann, Joshua R.; Ouyang, Lijing

doi:10.1016/j.dhjo.2018.08.009

Cited by 6 publications

(2 citation statements)

References 30 publications

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“…Previous research notes that people with a variety of longstanding physical disabilities have higher use of health-care services, [21][22][23] but prescription opioid filling within these conditions has not been previously investigated. We demonstrate the higher use of hospital-based health care by people with longstanding physical disabilities who fill an opioid prescription, but we are unable to explain the underlying reason for this finding with our data.…”

Section: Discussionmentioning

confidence: 99%

Associations Between Opioid Prescriptions and Use of Hospital-Based Services Among US Adults with Longstanding Physical Disability or Inflammatory Conditions Compared to Other Adults in the Medical Expenditure Panel Survey, 2010–2015

Turk¹,

McDermott²,

Zhang³

et al. 2023

JPR

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Purpose To investigate the association of filling opioid prescriptions with healthcare service utilization among a nationally representative sample of adults with disability. Materials and Methods The Medical Expenditure Panel Survey (MEPS) for 2010–2015, Panels 15–19, was used to identify adults who were prescribed opioids during each two-year period. We examined the data for associations between opioid prescription filling and the number of emergency department (ED) visits and hospitalizations. The participants were grouped as those with inflammatory conditions or with longstanding physical disability, and a comparison group of those without these conditions. Results and conclusions Opioid prescription filling differed among adults with inflammatory conditions and longstanding physical disability compared to the comparison group (44.93% and 40.70% vs 18.10%, respectively). For both groups of people with disability, the relative rates for an ED visit or hospitalization were significantly higher for those who filled an opioid prescription, compared to adults with the same conditions who did not fill an opioid prescription. People with a longstanding physical disability who filled an opioid prescription had the highest rate ratio of ED use and hospitalization. Results from this investigation demonstrate that opioid prescription filling among persons with inflammatory conditions and longstanding physical disabilities is associated with higher rates of ED visits and hospitalizations.

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Section: Discussionmentioning

confidence: 99%

Associations Between Opioid Prescriptions and Use of Hospital-Based Services Among US Adults with Longstanding Physical Disability or Inflammatory Conditions Compared to Other Adults in the Medical Expenditure Panel Survey, 2010–2015

Turk¹,

McDermott²,

Zhang³

et al. 2023

JPR

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“…Rare diseases have been found to account for a greater average length of stay than what the general inpatient population shows [ 10 , 11 ]. Specific rare diseases, like muscular dystrophies, spina bifida and fragile X syndrome were associated with a higher 30-day all-cause readmission rate [ 19 ]. Rare diseases seem to be associated with significant economic burden [ 20 ] and a disparity was found regarding healthcare costs and the proportion of the population with rare diseases [ 10 , 11 ].…”

Section: Discussionmentioning

confidence: 99%

Impact of single and combined rare diseases on adult inpatient outcomes: a retrospective, cross-sectional study of a large inpatient population

Blazsik

Beeler

Tarcak

et al. 2021

Orphanet J Rare Dis

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Background Little is known about the impact of rare diseases on inpatient outcomes. Objective To compare outcomes of inpatients with 0, 1, or > 1 rare disease. A catalogue of 628 ICD-10 coded rare diseases was applied to count rare diseases. Design Retrospective, cross-sectional study. Subjects 165,908 inpatients, Swiss teaching hospital. Main measures Primary outcome: in-hospital mortality. Secondary outcomes: length of stay (LOS), intensive care unit (ICU) admissions, ICU LOS, and 30-day readmissions. Associations with single and combined rare diseases were analyzed by multivariable regression. Key results Patients with 1 rare disease were at increased risk of in-hospital death (odds ratio [OR]: 1.80; 95% confidence interval [CI]: 1.67, 1.95), combinations of rare diseases showed stronger associations (OR 2.78; 95% CI 2.39, 3.23). Females with 1 rare disease had an OR of 1.69 (95% CI 1.50, 1.91) for in-hospital death, an OR of 2.99 (95% CI 2.36, 3.79) if they had a combination of rare diseases. Males had an OR of 1.85 (95% CI 1.68, 2.04) and 2.61 (95% CI 2.15, 3.16), respectively. Rare diseases were associated with longer LOS (for 1 and > 1 rare diseases: increase by 28 and 49%), ICU admissions (for 1 and > 1: OR 1.64 [95% CI 1.57, 1.71] and 2.23 [95% CI 2.01, 2.48]), longer ICU LOS (for 1 and > 1 rare diseases: increase by 14 and 40%), and 30-day readmissions (for 1 and > 1: OR 1.57 [95% CI 1.47, 1.68] and 1.64 [95% CI 1.37, 1.96]). Conclusions Rare diseases are independently associated with worse inpatient outcomes. This might be the first study suggesting even stronger associations of combined rare diseases with in-hospital deaths, increased LOS, ICU admissions, increased ICU LOS, and 30-day readmissions.

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Risk factors for unanticipated hospitalizations in children and youth with spina bifida at an urban children’s hospital: A cross-sectional study

Smith

Hudson²,

Betz³

et al. 2023

Disability and Health Journal

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30-day all-cause readmission rates among a cohort of individuals with rare conditions

Cited by 6 publications

References 30 publications

Associations Between Opioid Prescriptions and Use of Hospital-Based Services Among US Adults with Longstanding Physical Disability or Inflammatory Conditions Compared to Other Adults in the Medical Expenditure Panel Survey, 2010–2015

Associations Between Opioid Prescriptions and Use of Hospital-Based Services Among US Adults with Longstanding Physical Disability or Inflammatory Conditions Compared to Other Adults in the Medical Expenditure Panel Survey, 2010–2015

Impact of single and combined rare diseases on adult inpatient outcomes: a retrospective, cross-sectional study of a large inpatient population

Risk factors for unanticipated hospitalizations in children and youth with spina bifida at an urban children’s hospital: A cross-sectional study

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