2004
DOI: 10.1071/rdv16n1ab302
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302A MICROFLUIDIC DEVICE TO CONTROL Ca2+ SIGNALLING IN FERTILIZED AND NON FERTILIZED EGGS

Abstract: Following fertilization, eggs exhibit a series of repetitive increases in intracellular calcium that activate development. The developmental impact of the long-lasting series of Ca 2+ signals is still a subject of controversy. Although several studies using parthenogenetically activated eggs suggest that Ca 2+ dynamics affect post-implantation development, artificial stimulation of Ca 2+ signaling after ICSI in bovine eggs shows that development still remains poor in comparison to fertilized eggs. Such diverge… Show more

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