308-nm Excimer Lamp vs. Combination of 308-nm Excimer Lamp and 10% Liquor Carbonis Detergens in Patients With Scalp Psoriasis: A Randomized, Single-Blinded, Controlled Trial

Rattanakaemakorn, Ploysyne; Triyangkulsri, Korn; Iamsumang, Wimolsiri; Suchonwanit, Poonkiat

doi:10.3389/fmed.2021.677948

Cited by 4 publications

(2 citation statements)

References 37 publications

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“…Despite the complex disease etiology and our incomplete understanding of the relationship between these factors and hair loss, we presume that genetic predisposition, stress, and environmental factors affect immune activation and influence AA occurrence. [163][164][165][166][167][168][169] Further, novel targeted therapies that treat AA have been reviewed. However, a complete response without relapse remains challenging.…”

Section: Discussionmentioning

confidence: 99%

Alopecia Areata: An Autoimmune Disease of Multiple Players

Suchonwanit¹,

Kositkuljorn²,

Pomsoong³

2021

ITT

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Alopecia areata (AA) is an autoimmune disease of the hair follicles. It is characterized by a well-defined non-scarring alopecic patch or patches that may extend to the entire scalp or lead to total body hair loss. Due to its unpredictable clinical course, AA causes substantial psychological harm. Despite the high prevalence of this disease and extensive research, its exact pathomechanism is unclear, and current treatments have a high relapse rate that has deemed AA incurable. Over the past few decades, researchers have investigated multiple potential factors that may help alleviate its pathogenesis and provide effective treatment. Given its complex immunopathogenesis, AA is considered an autoimmune disease with multiple factors. This review gathers current evidence that emphasizes molecular mechanisms, possible causative etiologies, and targeted immunotherapies for AA. Understanding its underlying mechanisms may shed light on new strategies to effectively manage AA in the future.

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Section: Discussionmentioning

confidence: 99%

Alopecia Areata: An Autoimmune Disease of Multiple Players

Suchonwanit¹,

Kositkuljorn²,

Pomsoong³

2021

ITT

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“…This problem could be addressed by the advent of a core outcome set, ie, a minimum set of outcome measures that have been agreed upon to be important and necessarily reported in all clinical trials for a specific condition, 84 which should standardize the types of outcome measures used and promote comparability of results across trials evaluating the same disease. [85][86][87][88] Core outcome sets have been developed for several skin diseases, 89 but one for hair loss/nonscarring alopecia is still under development. 90 However, the Alopecia Areata Consensus of Experts (ACE) group has proposed a consensus on the outcome measures for AA patients, which recommended that measurement of HRQoL is required in clinical trials.…”

Section: Some Issues Concerning the Use Of Health-related Quality Of Life Measures In Alopecia Patientsmentioning

confidence: 99%

Measuring Patient Quality of Life Following Treatment for Alopecia

Thadanipon¹,

Suchonwanit²

2021

PPA

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Alopecia is a challenging problem for both physicians and patients in terms of diagnosis and treatment. Alopecia usually has negative effects on patients' emotional and psychological well-being. Several studies have examined the effect of alopecia on patients' health-related quality of life (HRQoL) and have consistently reported poor scores. However, deeper insight into the impact of alopecia on affected individuals and its measurement using HRQoL questionnaires is lacking in the literature. In this article, the methods for measuring the HRQoL of patients with alopecia were comprehensively reviewed. Their applications and limitations were also discussed.

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A pulsed bipolar current-mode power supply with high power factor in a single stage for dielectric barrier discharge application

Tang,

Zhou,

Chen

et al. 2024

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Purpose Dielectric barrier discharge (DBD) is widely used in the treatment of skin disease, surface modification of material and other fields of electronics. The purpose of this paper is to design a high-performance power supply with a compact structure for excimer lamps in electronics application. Design/methodology/approach To design a high-performance power supply with a compact structure remains a challenge for excimer lamps in electronics application, a current-source type power supply in a single stage with power factor correction (PFC) is proposed. It consists of an excitation voltage generation unit and a PFC unit. By planning the modes of the excitation voltage generation unit, a bipolar pulse excitation voltage with a high rising and falling rate is generated. And a high power factor (PF) on the AC side is achieved by the interaction of a non-controlled rectifier and two inductors. Findings The experimental results show that not only a high-frequency and high-voltage bipolar pulse excitation voltage with a high average rising and falling rate (7.51GV/s) is generated, but also a high PF (0.992) and a low total harmonic distortion (5.54%) is obtained. Besides, the soft-switching of all power switches is realized. Compared with the sinusoidal excitation power supply and the current-source power supply, the proposed power supply in this paper can take advantage of the potential of excimer lamps. Originality/value A new high-performance power supply with a compact structure for DBD type excimer lamps is proposed. The proposed power supply can work stably in a wide range of frequencies, and the smooth regulation of the discharge power of the excimer lamp can be achieved by changing the switching frequency. The ideal excitation can be generated, and the soft switching can be realized. These features make this power supply a key player in the outstanding performance of the DBD excimer lamps application.

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308-nm Excimer Lamp vs. Combination of 308-nm Excimer Lamp and 10% Liquor Carbonis Detergens in Patients With Scalp Psoriasis: A Randomized, Single-Blinded, Controlled Trial

Cited by 4 publications

References 37 publications

Alopecia Areata: An Autoimmune Disease of Multiple Players

Alopecia Areata: An Autoimmune Disease of Multiple Players

Measuring Patient Quality of Life Following Treatment for Alopecia

A pulsed bipolar current-mode power supply with high power factor in a single stage for dielectric barrier discharge application

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