30days and midterm outcomes of patients undergoing percutaneous replacement of aortic valve according to their renal function: A multicenter study

D’Ascenzo, Fabrizio; Moretti, Claudio; Salizzoni, Stefano; Bollati, Mario; D’Amico, Maurizio; Ballocca, Flavia; Giordana, Francesca; Barbanti, Marco; Ussia, Gian Paolo; Brambilla, Nedy; Bedogni, Francesco; Biondi‐Zoccai, Giuseppe; Tamburino, Corrado; Gaïta, Fiorenzo; Sheiban, Imad

doi:10.1016/j.ijcard.2012.04.161

Cited by 53 publications

(49 citation statements)

References 24 publications

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“…10,11 In contrast, other studies did not find a significant relationship between CKD and worse outcomes. 8,9,12,13 Consistent with this background, in the present study, we pooled the available evidence on this issue confirming the negative prognostic impact of advanced CKD, but also demonstrating for the first time that CKD stage 3 is associated with a significant increase of early and late mortality. Frequently, patients with CKD, particularly those at an advanced stage of disease, have more cardiovascular risk factors and experience increased cardiovascular mortality.…”

Section: Discussionsupporting

confidence: 87%

“…[10][11][12][13][17][18][19][20][21] The characteristics of the included studies are reported in Table 1. There was no significant variability in the CKD definitions used across the studies.…”

Section: Resultsmentioning

confidence: 99%

“…In particular, the higher risk of mortality has been suggested in patients with more severe CKD. [10][11][12]17,20 However, recent data showed that advanced CKD (stages 4-5), but not moderate CKD (stage 3), was a predictor of early and late mortality. 10,11 In contrast, other studies did not find a significant relationship between CKD and worse outcomes.…”

Section: Discussionmentioning

confidence: 99%

“…12,13 On this background, given the contrasting evidence and the latest literature in this field, there is a clinical and scientific rationale to investigate the impact of preoperative CKD on the clinical outcomes of patients undergoing TAVI.…”

mentioning

confidence: 99%

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Moderate and Severe Preoperative Chronic Kidney Disease Worsen Clinical Outcomes After Transcatheter Aortic Valve Implantation

Gargiulo

Capodanno

Sannino

et al. 2015

Circ: Cardiovascular Interventions

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T ranscatheter aortic valve implantation (TAVI) has emerged as an alternative to surgery therapy for severe aortic stenosis.1,2 The detrimental impact of baseline chronic kidney disease (CKD) on worsening the prognosis of patients undergoing surgical aortic valve replacement is well established. 3,4 Conversely, this remains a debated issue in patients undergoing TAVI.Mixed evidences are available regarding the relationship between baseline CKD and clinical outcomes in TAVI, and patients with CKD were typically under-represented in TAVI trials. On the other hand, CKD showed to be an independent predictor of mortality at 1-year after TAVI in some registries, [5][6][7][8] but not in others. 9 The degree of CKD, which exposes to the highest risk is also a matter of debate: recent data suggest that CKD stage 4 and 5, but not stage 3, are predictors of 30-day and late mortality after TAVI.10,11 Finally, cross-sectional studies failed to show a significant impact of CKD on mortality. 12,13 On this background, given the contrasting evidence and the latest literature in this field, there is a clinical and scientific rationale to investigate the impact of preoperative CKD on the clinical outcomes of patients undergoing TAVI. Methods Study SelectionThe study was designed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses requirements. MEDLINE, Cochrane, ISI Web of Science, and SCOPUS databases were searched Background-There is a conflicting evidence on safety and efficacy of transcatheter aortic valve implantation in patients with preoperative chronic kidney disease (CKD). Therefore, we conducted a meta-analysis on the impact of CKD on outcomes after transcatheter aortic valve implantation. Methods and Results-Nine

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Section: Discussionsupporting

confidence: 87%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Moderate and Severe Preoperative Chronic Kidney Disease Worsen Clinical Outcomes After Transcatheter Aortic Valve Implantation

Gargiulo

Capodanno

Sannino

et al. 2015

Circ: Cardiovascular Interventions

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“…Schnabel et al [28] correlated both the lowest eGFR and a change in eGFR within the first 72 h following TAVI as predictors of both 30-day and 1-year mortality in their recent study. This improvement in renal function following TAVI was also described by D'Ascenzo et al [42] who describe the greatest improvement in those with poorer baseline function.…”

Section: Effect Of Tavi On Renal Functionsupporting

confidence: 74%

92 Transcatheter Aortic Valve Implantation in Patients with Pre-existing Chronic Kidney Disease

Rahman

Sharma

Brecker

2015

Heart

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Background:We investigated the effect of chronic kidney disease (CKD) on morbidity and mortality following transcatheter aortic valve implantation (TAVI) including patients on haemodialysis, often excluded from randomised trials. Conclusion: TAVI is a safe, acceptable treatment for patients with pre-existing CKD, however caution must be exercised, particularly in patients with pre-existing diabetes mellitus and elevated pre-operative serum creatinine levels as this confers a greater risk of AKI development, which is associated with increased shortterm post-operative mortality.

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Kidney injury and mortality after transcatheter aortic valve implantation in a routine clinical cohort

Schnabel¹,

Seiffert²,

Wilde³

et al. 2014

Cathet Cardio Intervent

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30days and midterm outcomes of patients undergoing percutaneous replacement of aortic valve according to their renal function: A multicenter study

Cited by 53 publications

References 24 publications

Moderate and Severe Preoperative Chronic Kidney Disease Worsen Clinical Outcomes After Transcatheter Aortic Valve Implantation

Moderate and Severe Preoperative Chronic Kidney Disease Worsen Clinical Outcomes After Transcatheter Aortic Valve Implantation

92 Transcatheter Aortic Valve Implantation in Patients with Pre-existing Chronic Kidney Disease

Kidney injury and mortality after transcatheter aortic valve implantation in a routine clinical cohort

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