2012
DOI: 10.1097/01.wox.0000412074.83279.36
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311 Pathogenesis of Radiation-induced Pneumonitis in Patients with Chronic Obstructive Pulmonary Disease

Abstract: BackgroundChest radiation is a common therapeutic approach in the management of lung cancer, as well as in other malignancies, rendering radiation-induced pneumonitis a rather commonly reported adverse event. A large proportion of patients undergoing radiation have underlying chronic obstructive pulmonary disease (COPD). We aim to elucidate the pathogenetic pathways implicated in radiation-induced pneumonitis particularly in this subgroup of patients.MethodsA literature search was performed in PubMed to identi… Show more

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