317 Results of a Large RCT Testing the Effect of Cognitive Behavior Therapy on School Absences, Quality of Life and Flares in Pediatric IBD

Documenting an epidemic of suffering: low health-related quality of life among transgender youth

“…It is important to utilize these results to develop interventions to improve QoL for TGN youth. Interventions to improve HRQOL for children and youth with other conditions have been successful[39–43]. As the number of TGN youth increases, children for whom poor quality of life is a major factor will continue to present to community physicians as well as specialists in TGN care.…”

The impact of integrating behavioral health services into pediatric subspecialty care: A systematic review

“…See Supporting Information S1: Digital Content 2 for detailed information regarding sample characteristics. Ten studies focused on patients with IBD, [28][29][30][31][32][33][34][35][36][37] and eight on functional GI disorders. [38][39][40][41][42][43][44][45] The weighted average age of all participants was 13.89 years old.…”

“…The most common approach to micro-level integration was to recruit participants within a pediatric gastroenterology clinic to participate in a formal research study investigating a behavioral health intervention. Fourteen of those provided treatment based on a cognitive-behavioral therapy (CBT) model, 28,[30][31][32][33][34][35][36][37][38][39]42,43,45 one provided problem-solving skills training, 29 and one provided gut-focused hypnotherapy. 44 Among the micro-level studies, six reported services were funded by foundations or charitable institutions, [28][29][30]34,35,45 five by federal research grants, 32,37,38,42,44 one from a pharmaceutical company, 31 one through a pediatric health system research grant, 43 and two through a combination of these sources.…”

“…The three studies failing to show any differences were (1) a study of CBT for (N = 86) youth with functional abdominal pain disorder (FAPD); 43 (2) a study of an intervention based on Social Learning Theory and CBT for (N = 185) youth with IBD 32 ; and (3) a study of CBT for (N = 70) youth with IBD and depression or anxiety. 34 Of the RCTs testing behavioral health against minimal additional treatment beyond typical gastroenterological care, six directly assessed QOL, 28,29,[32][33][34]45 seven assessed psychological symptoms, 28,[32][33][34]36,39,45 and two assessed child functioning. 36,43 The evidence for the impact of behavioral health integration on depression symptoms was the most consistent, with 60.0% of studies finding statistically significant treatment effects.…”

“…40 Half of the studies reported on integration strategies that offered services to all patients regardless of the presence of mental health symptoms. [29][30][31][32]40,41,[43][44][45] The other half offered services only to those patients with co-occurring mental health symptoms. 28,[33][34][35][36][37][38][39]42 Five studies enrolled youth with depression symptoms, 28,33,[35][36][37] three with anxiety symptoms, 38,39,42 and one with either depression or anxiety symptoms.…”