32.2.6 Monofunctionalized Allenes (Update 2018)

Abstract

This chapter is an update to Science of Synthesis Section 32.2, covering the synthesis of allenes bearing one heteroatom substituent on the cumulated diene core. It covers the literature from 2008 to 2016. Many routes to these allenes start from alkynes, enynes, or propargylic systems and the syntheses proceed through substitution/rearrangement, but reactions involving the modification of an existing allene core are also included. In recent years, the synthesis of enantiomerically pure allenes has been of particular interest.