33 Comparative evaluation of antitumoral efficiency of various photosensitizers at photodynamic therapy of sarcoma M-1

Efficacy of photodynamic therapy with intraperitoneal introduction photosensitizer Amidoaminchlorine on rat sarcoma M1 model was studied. The aim of this study was to determine minimum effective dose of photosensitizer and parameters of laser radiation for achievement of tumor full regress. Dynamics of photosensitizer accumulation in tumor and healthy tissues was studied to definite the time of photodynamic therapy. Antitumor efficacy different doses of photosensitizer and various parameters of laser radiation were investigated. As a result, optimal term of photodynamic therapy, photosensitizer minimum effective dose and parameters of laser irradiation were established.

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Photodynamic Therapy of Rat Sarcoma M-1 With Photosensitizer Amidoaminchlorine

Kaplan

Malygina

Пономарева

et al. 2015

Rossijskij bioterapevtičeskij žurnal

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33 Comparative evaluation of antitumoral efficiency of various photosensitizers at photodynamic therapy of sarcoma M-1

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Photodynamic Therapy of Rat Sarcoma M-1 With Photosensitizer Amidoaminchlorine

Photodynamic Therapy of Rat Sarcoma M-1 With Photosensitizer Amidoaminchlorine

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