2006
DOI: 10.1016/s0168-8278(06)80357-0
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357 Macrophage activation promotes invasive properties of hepatocellular carcinoma cells through destablization of the E-cadherin/ B-catenin complex

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“…In addition, methylation or heterozygous deletion of E-cad was closely related to the progression of liver cancer ( 31 ). Furthermore, Lin et al ( 32 ) confirmed that MMP-2 and its activator membrane type 1-MMP are highly expressed and serve a role in the differentiation of hepatic cancer. Therefore, atractylon may inhibit the invasion and migration of hepatic carcinoma cells.…”
Section: Discussionmentioning
confidence: 97%
“…In addition, methylation or heterozygous deletion of E-cad was closely related to the progression of liver cancer ( 31 ). Furthermore, Lin et al ( 32 ) confirmed that MMP-2 and its activator membrane type 1-MMP are highly expressed and serve a role in the differentiation of hepatic cancer. Therefore, atractylon may inhibit the invasion and migration of hepatic carcinoma cells.…”
Section: Discussionmentioning
confidence: 97%