360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity

Butler, Joseph S.; Lui, Darren F; Malhotra, Karan; Suarez-Huerta, M.L.; Yu, Haiming; Selvadurai, Susanne; Agu, Obiekezie; Molloy, Sean

doi:10.1177/2192568218814531

Cited by 9 publications

(10 citation statements)

References 14 publications

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“…A circumferential surgical approach has been postulated to be a more efficacious method of achieving lumbar lordosis in ASD patients. Butler et al 24 (P < 0.001), with a significant reduction in visual analogue scale and oswestry disability index scores (both P < 0.001), and improvement in euroQol-5D scores (P = 0.02). 25 It has also been proposed that circumferential fusion produces a more harmonious correction of alignment and allows for a more cranial lowest instrumented vertebra without sacrificing spinal alignment.…”

Section: Discussionmentioning

confidence: 91%

A Systematic Review of Risk Factors Associated With Distal Junctional Failure in Adult Spinal Deformity Surgery

McDonnell

Ahern

Wagner

et al. 2021

Clinical Spine Surgery: A Spine Publication

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Background: The surgical management of adult spinal deformity (ASD) is a major surgical undertaking associated with considerable perioperative risk and a substantial complication profile. Although the natural history and risk factors associated with proximal junctional kyphosis (PJK) and proximal junctional failure are widely reported, distal junctional failure (DJF) is less well understood.Study Design: A systematic review was carried out.Objectives: The primary objective is to identify the risk factors associated with DJF. The secondary objective is to delineate the incidence rate and causative factors associated with DJF.Methods: A systematic review of articles in Medline/PubMed and The Cochrane Library databases was performed according to preferred reporting items for systematic reviews and metaanalyses guidelines. Data was collated to determine the prevalence of DJF and overall revision rates, and identify potential risk factors for development of DJF.Results: Twelve studies were included for systematic review. There were 81/2261 (3.6%) cases of DJF. Overall, DJF represented 27.3% of all revision surgeries. Anterior-posterior surgery had a reduced incidence of postoperative DJF [5.0% vs. 8.7%; P = 0.08; relative risk (RR) = 1.73], as did patients below 60 years of age at the time of surgery (2.9% vs. 3.9%; P = 0.09; RR = 1.34). There was a higher incidence of DJF among those patients who received interbody fusion (9.9% vs. 5.1%; P = 0.06; RR = 1.93) compared with those who did not. However, none of these findings reached statistical significance. There were significantly more rates of DJF for fusions ending on L5 compared with constructs fused to the sacrum (11.7% vs. 3.6%; P = 0.02; RR = 3.28).Conclusions: Cohorts 60 years and above of age at the time of surgery and patients managed with posterior-only fusion or interbody fusion have increased incidences of DJF. Fusion to L5 instead of the sacrum significantly influences DJF rates. However, the quality of available evidence is low and further highquality studies are required to more robustly analyze the clinical, radiographic, and surgical risk factors associated with the development of DJF after ASD surgery.

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Section: Discussionmentioning

confidence: 91%

A Systematic Review of Risk Factors Associated With Distal Junctional Failure in Adult Spinal Deformity Surgery

McDonnell

Ahern

Wagner

et al. 2021

Clinical Spine Surgery: A Spine Publication

Self Cite

View full text Add to dashboard Cite

show abstract

“…Though moderate satisfactory clinical results were revealed and significant relieved back and leg pain was only reported in 46% of patients, 85% of patients had possessed remarkable improvement in their working-status post-surgery 1 year [131]. Meanwhile, Lebhar et al [132] and Butler et al [133] respectively reported reliable clinical, functional and radiographic results after the application of porous Ta implant for lumbar intervertebral fusion in their retrospective cohort studies.…”

Section: Spine Intervertebral Fusionmentioning

confidence: 99%

The Clinical Application of Porous Tantalum and Its New Development for Bone Tissue Engineering

Huang¹,

Pan²,

Qiu³

2021

Preprint

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Porous tantalum (Ta) is a promising biomaterial and has been applied in orthopedics and dentistry for nearly two decades. The high porosity and interconnected pore structure of porous Ta promise fine bone ingrowth and new bone formation within the inner space, which further guarantee rapid osteointegration and bone-implant stability in long term. Porous Ta has high wettability and surface energy that can facilitate adherence, proliferation and mineralization of osteoblasts. Meanwhile, low elastic modulus and high friction coefficient of porous Ta can effectively avoid stress shield effect, minimize marginal bone loss and ensure primary stability. Accordingly, the satisfactory clinical application of porous Ta based implants or prostheses are mainly derived from its excellent biological and mechanical properties. With the advent of additive manufacturing, personalized porous Ta based implants or prostheses have shown their clinical value in the treatment of individual patient who need specially designed implant or prosthesis. In addition, many modification methods have been introduced to enhance the bioactivity and antibacterial property of porous Ta with promising in vitro and in vivo research results. In any case, choosing suitable patients is of great importance to guarantee surgical success after porous Ta insertion.

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“…Though moderate satisfactory clinical results were revealed and significant relief of back and leg pain was only reported in 46% of patients, 85% of patients showed remarkable improvement in their working-status at 1 year post-surgery [ 145 ]. Meanwhile, Lebhar et al [ 146 ] and Butler et al [ 57 ], respectively, reported reliable clinical, functional and radiographic results after the application of porous Ta implant for lumbar intervertebral fusion in their retrospective cohort studies.…”

Section: Clinical Application Of Porous Ta In Orthopedics and Dentistrymentioning

confidence: 99%

“…Porous Ta lumbar interbody fusion cage ( b ) Reprinted from ref. [ 57 ], porous Ta rod ( c ) Reprinted from ref. [ 58 ] and dental implant ( d ) Reprinted from ref.…”

Section: Figurementioning

confidence: 99%

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The Clinical Application of Porous Tantalum and Its New Development for Bone Tissue Engineering

2021

View full text Add to dashboard Cite

Porous tantalum (Ta) is a promising biomaterial and has been applied in orthopedics and dentistry for nearly two decades. The high porosity and interconnected pore structure of porous Ta promise fine bone ingrowth and new bone formation within the inner space, which further guarantee rapid osteointegration and bone–implant stability in the long term. Porous Ta has high wettability and surface energy that can facilitate adherence, proliferation and mineralization of osteoblasts. Meanwhile, the low elastic modulus and high friction coefficient of porous Ta allow it to effectively avoid the stress shield effect, minimize marginal bone loss and ensure primary stability. Accordingly, the satisfactory clinical application of porous Ta-based implants or prostheses is mainly derived from its excellent biological and mechanical properties. With the advent of additive manufacturing, personalized porous Ta-based implants or prostheses have shown their clinical value in the treatment of individual patients who need specially designed implants or prosthesis. In addition, many modification methods have been introduced to enhance the bioactivity and antibacterial property of porous Ta with promising in vitro and in vivo research results. In any case, choosing suitable patients is of great importance to guarantee surgical success after porous Ta insertion.

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360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity

Cited by 9 publications

References 14 publications

A Systematic Review of Risk Factors Associated With Distal Junctional Failure in Adult Spinal Deformity Surgery

A Systematic Review of Risk Factors Associated With Distal Junctional Failure in Adult Spinal Deformity Surgery

The Clinical Application of Porous Tantalum and Its New Development for Bone Tissue Engineering

The Clinical Application of Porous Tantalum and Its New Development for Bone Tissue Engineering

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