3D cardiac wall thickening assessment for acute myocardial infarction

Khalid, Amirah; Chan, Bee Ting; Lim, Einly; Liew, Yih Miin

doi:10.1088/1757-899x/210/1/012001

Cited by 1 publication

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, infarct zone of the myocardium tended to become rigid and thinner as a result of injury and necrosis. [ 40 ] Therefore, regional assessment of WMSI, infarct size, wall thickening, and myocardial perfusion might provide a mean to improve clinical diagnosis for better patient outcomes.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Impact of bone marrow mononuclear cells therapy on left ventricular function in patients with ST-elevated myocardial infarction

Wang¹,

Han²,

Li³

et al. 2018

Medicine

View full text Add to dashboard Cite

Background:Bone marrow mononuclear cell (BMMNC) therapy has been used as an adjunctive treatment in patients with ST-elevated myocardial infarction (STEMI). However, the therapeutic efficacy of this approach remains controversial. The present meta-analysis is aimed to evaluate the impact of cell therapy on left ventricular function after STEMI.Methods:We searched through PubMed and EMBASE databases till 2017 for all relevant publications using certain search terms. Randomized controlled trials investigating the effect of BMMNC therapy in patients with STEMI who underwent percutaneous coronary intervention were selected. Wall motion score index (WMSI), infarct size, wall thickening, and myocardial perfusion were our endpoints.Results:A total of 24 trials with 1536 patients were included in our study. Overall, as observed in our data, cell therapy reduced infarct size by −2.32 (95% confidence interval [CI] −4.03, −0.62; P = .007; I2 = 24%) and improved myocardial perfusion by −3.04 (95% CI −3.94, −2.15; P < .001; I2 = 0%). However, there was no significant difference between treatment group and control group in WMSI or wall thickening.Conclusion:Intracoronary BMMNC infusion is safe for patients with STEMI. It is also associated with improvement of infarct size and myocardial perfusion. Further multicenter randomized trials should be conducted to validate the therapeutic efficacy of this treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

“…[ 42 ] Another study showed that wall thickening was closely related to cardiac function and could reveal regional abnormality triggered by AMI. [ 40 ]…”

Section: Discussionmentioning

confidence: 99%