2023
DOI: 10.1021/acsbiomaterials.3c01437
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3D Coculture between Cancer Cells and Macrophages: From Conception to Experimentation

Rohan Quoniou,
Emmanuel Moreau,
Florent Cachin
et al.

Abstract: A tumor is a complex cluster with many types of cells in the microenvironment that help it grow. Macrophages, immune cells whose main role is to maintain body homeostasis, represent in the majority of cancers the most important cell population. In this context, they are called tumor-associated macrophages (TAMs) because of their phenotype, which contributes to tumor growth. In order to limit the use of animals, there is a real demand for the creation of in vitro models able to represent more specifically the c… Show more

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