3D-flow simulation and optimization of a cross flow filtration with rotating discs

Rainer, M.; Höflinger, Wilhelm; Koch, W.; Pongratz, Elmar; Oechsle, Dietmar

doi:10.1016/s1383-5866(01)00123-x

Cited by 10 publications

(3 citation statements)

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“…Based on the Russian experience and design improvements identified, a "rad hardened" unit is believed to be operable for five years. The 3D flow regime of a crossflow filter with horizontal rotating discs was examined and modeled (Rainer 2002). …”

Section: Centrifugal Filtration (Rotary Microfilter)mentioning

confidence: 99%

Hanford Supplemental Treatment: Literature and Modeling Review of SRS HLW Salt Dissolution and Fractional Crystallization

Choi¹,

Flach²,

Martino³

et al. 2005

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Section: Centrifugal Filtration (Rotary Microfilter)mentioning

confidence: 99%

Hanford Supplemental Treatment: Literature and Modeling Review of SRS HLW Salt Dissolution and Fractional Crystallization

Choi¹,

Flach²,

Martino³

et al. 2005

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“…Monfared et al [27] investigated the effect of presence of baffles in the membrane tube by using the CFD method and they found a considerable enhancement in the filtration performances. Rainer et al [28] explored by numerical simulations the effect of the presence of rotating discs inside the membrane tube and they obtained a significant augmentation of the filtration execution. Ameur and Sahel [29] inserted hemispherical baffles in a membrane tube and explored numerically the effect of their arrangements (right and left orientations, RO and LO, respectively).…”

Section: Introductionmentioning

confidence: 99%

Numerical Investigation of the Effect of Blower Baffles on the Performance of Membrane Tubes for Water Treatment

Sahel¹,

Boudaoud²,

Ameur³

et al. 2021

AMS

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Effects of blower shaped baffles on the fluid dynamics and filtration flux in a membrane tube are numerically explored. Both the staggered and inline arrangements of baffles are studied. The carbonate calcium suspensions with a concentration of 5 g/L were used as a working medium. The efficiency of filtration was determined via the calculation of velocity of fluid particles, wall shear stresses and static pressure. An increase in the shear stresses on the tube surface, as well as a formation of fluid eddies were observed with the presence an array of blower baffles, resulting thus in a significant improvement of the filtration performance. The case of the staggered baffles with pith ratio of L/D = 1 and Re = 15,000 achieved an increase in the filtration flux rate by 42% and 12%, compared with unbaffled and tube with baffle orientation angle of 180°, respectively.

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“…CFD is finding increasing use in the modeling of biological processes, including bioreactors (Davidson et al, 2003;Williams et al, 2002) and filtration units (Rainer et al, 2002;Taha and Cui, 2002). Recently, Castilho and Anspach (2003) used CFD to model a dynamic filter for cell harvesting and recycle that utilizes a rotor assembly in the fluid chamber.…”

Section: Introductionmentioning

confidence: 99%

Optimizing the rotor design for controlled-shear affinity filtration using computational fluid dynamics

Francis¹,

Martinez²,

Taghipour³

et al. 2006

Biotechnol. Bioeng.

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Controlled shear affinity filtration (CSAF) is a novel integrated processing technology that positions a rotor directly above an affinity membrane chromatography column to permit protein capture and purification directly from cell culture. The conical rotor is intended to provide a uniform and tunable shear stress at the membrane surface that inhibits membrane fouling and cell cake formation by providing a hydrodynamic force away from and a drag force parallel to the membrane surface. Computational fluid dynamics (CFD) simulations are used to show that the rotor in the original CSAF device (Vogel et al., 2002) does not provide uniform shear stress at the membrane surface. This results in the need to operate the system at unnecessarily high rotor speeds to reach a required shear stress of at least 0.17 Pa at every radial position of the membrane surface, compromising the scale-up of the technology. Results from CFD simulations are compared with particle image velocimetry (PIV) experiments and a numerical solution for low Reynolds number conditions to confirm that our CFD model accurately describes the hydrodynamics in the rotor chamber of the CSAF device over a range of rotor velocities, filtrate fluxes, and (both laminar and turbulent) retentate flows. CFD simulations were then carried out in combination with a root-finding method to optimize the shape of the CSAF rotor. The optimized rotor geometry produces a nearly constant shear stress of 0.17 Pa at a rotational velocity of 250 rpm, 60% lower than the original CSAF design. This permits the optimized CSAF device to be scaled up to a maximum rotor diameter 2.5 times larger than is permissible in the original device, thereby providing more than a sixfold increase in volumetric throughput.

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3D-flow simulation and optimization of a cross flow filtration with rotating discs

Cited by 10 publications

References 0 publications

Hanford Supplemental Treatment: Literature and Modeling Review of SRS HLW Salt Dissolution and Fractional Crystallization

Hanford Supplemental Treatment: Literature and Modeling Review of SRS HLW Salt Dissolution and Fractional Crystallization

Numerical Investigation of the Effect of Blower Baffles on the Performance of Membrane Tubes for Water Treatment

Optimizing the rotor design for controlled-shear affinity filtration using computational fluid dynamics

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