3D hotspot matrix of Au nanoparticles on Au island film with a spacer layer of dithiol molecules for highly sensitive surface-enhanced Raman spectroscopy

Lee, Dong Hoon; Kim, Dae Yu

doi:10.1038/s41598-021-01742-0

Cited by 4 publications

(2 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The enhancement factor (EF) is an important parameter to compute the enhancement ability of any SERS substrate. Thus, the EF of the sarcosine adsorbed on the surface of the SiO 2 @Ag platform was estimated using Equation (1), which is also in good agreement with the previously reported works, given below [19,42,43];…”

Section: Eer Review 7 Of 16supporting

confidence: 87%

Silica Nanospheres Coated Silver Islands as an Effective Opto-Plasmonic SERS Active Platform for Rapid and Sensitive Detection of Prostate Cancer Biomarkers

et al. 2022

View full text Add to dashboard Cite

The in vitro diagnostics of cancer are not represented well yet, but the need for early-stage detection is undeniable. In recent decades, surface-enhanced Raman spectroscopy (SERS) has emerged as an efficient, adaptable, and unique technique for the detection of cancer molecules in their early stages. Herein, we demonstrate an opto-plasmonic hybrid structure for sensitive detection of the prostate cancer biomarker sarcosine using silica nanospheres coated silver nano-islands as a facile and efficient SERS active substrate. The SERS active platform has been developed via thin (5–15 nm) deposition of silver islands using a simple and cost-effective Radio Frequency (RF) sputtering technique followed by the synthesis and decoration of silica nanospheres (~500 nm) synthesized via Stober’s method. It is anticipated that the coupling of Whispering Gallery Modes and photonic nano-jets in SiO2 nanospheres induce Localized Surface Plasmon Resonance (LSPR) in Ag nano-islands, which is responsible for the SERS enhancement. The as-fabricated SERS active platform shows a linear response in the physiological range (10 nM to 100 μM) and an extremely low limit of detection (LOD) of 1.76 nM with a correlation coefficient of 0.98 and enhancement factor ~2 × 107. The findings suggest that our fabricated SERS platform could be potentially used for the rapid detection of bio-chemical traces with high sensitivity.

show abstract

Section: Eer Review 7 Of 16supporting

confidence: 87%

Silica Nanospheres Coated Silver Islands as an Effective Opto-Plasmonic SERS Active Platform for Rapid and Sensitive Detection of Prostate Cancer Biomarkers

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Figure c shows that GO is better dispersed in the solvent than rGO. According to the literature, a hot junction is formed when the gap between the nanoparticles is <10 nm. − In this sense, the hot spot effect can be produced along the z -axis direction of the TAgNPs/GO nanohybrid system, thereby enhancing the intensity of the SERS signal. Therefore, the SERS signal enhancement effect of TAgNPs/GO was better than that of TAgNPs/rGO.…”

Section: Resultsmentioning

confidence: 99%

Triangular Silver Nanoplates/Graphene Oxide Nanohybrids on Flexible Substrates for Detection of Bacteria via Surface-Enhanced Raman Spectroscopy

Chen

Chang

Wang

et al. 2023

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

In this study, triangular silver nanoplates (TAgNPs) with various sizes were prepared using a seed-mediated growth method. The TAgNPs/GO and TAgNPs/rGO nanohybrids were synthesized by using graphene oxide (GO) and reduced graphene oxide (rGO), respectively. Furthermore, nanohybrid surface-enhanced Raman scattering (SERS) substrates with high sensitivity have been prepared that can be used for the SERS-based detection of biological targets. Our experimental results show that the SERS signals were enhanced when the TAgNPs have a shorter edge length. Such an enhancement was further promoted by the lightning rod effect at the sharp tips of the TAgNPs. Moreover, GO has good dispersibility in water, and the thickness of GO flakes is ∼5 nm. The TAgNPs/GO nanohybrid exhibits an improved signal enhancement effect when compared to the TAgNPs because of the hot spot excited along the z-axis. In addition, many oxygen-containing moieties on the surface of GO (e.g., hydroxyl, carboxylic, and epoxide moieties) can form hydrogen bonds with Pluronic F-127-coated TAgNPs, which improves the dispersion of the TAgNPs on the surface of GO. The π–π stacking interactions formed between GO and adenine can also improve the stability of the molecular structure, thereby increasing the adsorption of adenine molecules on the substrate. The limit of detection (LOD) and SERS enhancement factor for adenine were determined to be 10–9 M and 1.09 × 108 using TAgNPs/GO (40:1 w/w), respectively. For the detection of bacteria, the SERS technique can effectively reduce the detection time and achieve good detection results, even with low detection limits. The LOD for Staphylococcus aureus is only 102 CFU/mL using TAgNPs/GO. This result revealed that TAgNPs/GO has great market potential as a SERS substrate and can be widely used for the detection of bacteria.

show abstract

Mechanically Flexible, Large-Area Fabrication of Three-Dimensional Dendritic Au Films for Reproducible Surface-Enhanced Raman Scattering Detection of Nanoplastics

Carreón,

Rodríguez-Hernández,

Serrano de la Rosa

et al. 2024

ACS Sens.

View full text Add to dashboard Cite

3D hotspot matrix of Au nanoparticles on Au island film with a spacer layer of dithiol molecules for highly sensitive surface-enhanced Raman spectroscopy

Cited by 4 publications

References 50 publications

Silica Nanospheres Coated Silver Islands as an Effective Opto-Plasmonic SERS Active Platform for Rapid and Sensitive Detection of Prostate Cancer Biomarkers

Silica Nanospheres Coated Silver Islands as an Effective Opto-Plasmonic SERS Active Platform for Rapid and Sensitive Detection of Prostate Cancer Biomarkers

Triangular Silver Nanoplates/Graphene Oxide Nanohybrids on Flexible Substrates for Detection of Bacteria via Surface-Enhanced Raman Spectroscopy

Mechanically Flexible, Large-Area Fabrication of Three-Dimensional Dendritic Au Films for Reproducible Surface-Enhanced Raman Scattering Detection of Nanoplastics

Contact Info

Product

Resources

About