Introduction: Most of the implants used for total knee arthroplasty in Asian patients have been produced based on anthropometry of Western people. Anthropometric studies have shown that there are significant variations in knee morphology between the Asian and Western population. Data of Indian knee morphometry of healthy and non osteoarthritic knee was lacking. Objective of this study was to study the knee anthropometry of Indian population and its comparison with other ethnic groups and current TKA Implants. Materials and Methods: 60 patients, 29 female and 31 male with peri-articlar knee injuries from the period of June 2016 to November 2016 were studied. 3D reconstruction of normal knee of the patients undergoing CT scan for injured knee was done. Measurement of the mediolateral width, anteroposterior width and aspect ratio of distal femur and proximal tibia was done. Data was compared with other ethnic groups and currently available and commonly used knee systems. Results: Indian females were found to have significantly (p>0.01) smaller dimensions of femur and tibia than Indian males and both had smaller aspect ratios than the Western population. Also study suggests that there is a morphological mismatch between commonly used implants and Indian knees. Conclusion: Our study suggests that why Western implant mismatches when implanted in Indian patients. Also this study provides definite rationale for designing total knee prosthesis, especially a gender-specific design suitable for the Indian population.