3D printed complex tissue construct using stem cell-laden decellularized extracellular matrix bioinks for cardiac repair

Jang, Jinah; Hun-Jun, Park; Kim, Seok-Won; Kim, Hee‐Jin; Park, Ju Young; Na, Soo Jin; Kim, Hyeon Ji; Park, Moon Nyeo; Choi, Seung Hyun; Park, Sun Hwa; Kim, Sung Won; Kwon, Sang‐Mo; Kim, Pum-Joon; Cho, Dong‐Woo

doi:10.1016/j.biomaterials.2016.10.026

Cited by 561 publications

(394 citation statements)

References 40 publications

Supporting

Mentioning

392

Contrasting

Unclassified

Order By: Relevance

“…Myocardial regeneration likely requires not only a "regenerative" matrix profile, but also local secretion of a yet-undefined combination of cytokines and growth factors, and activation of pathways that enhance plasticity of progenitor cell populations (146). Third, in several cell therapy studies in mammalian models of cardiac injury, application of matrix-based patches containing progenitor cells showed enhanced effectiveness (147,148). It has been suggested that application of matrix patches that recapitulate the regenerative environment of the embryonic myocardium may increase TSP-1, may drive the fate of cardiac interstitial cells toward a fibroblast phenotype promoting fibrotic remodeling.…”

Section: The Cardiac Ecm In Metabolic Diseasementioning

confidence: 99%

The extracellular matrix in myocardial injury, repair, and remodeling

Frangogiannis¹

2017

Journal of Clinical Investigation

400

318

View full text Add to dashboard Cite

Section: The Cardiac Ecm In Metabolic Diseasementioning

confidence: 99%

The extracellular matrix in myocardial injury, repair, and remodeling

Frangogiannis¹

2017

Journal of Clinical Investigation

400

318

View full text Add to dashboard Cite

“…However, depreciated migration of implanted cells was also observed. Additionally, a dECM bioink was used to print the cardiac tissues [190,191] (Fig. 4A–I).…”

Section: Regeneration and Pharmacological Study Of 3d Bioprintedcardimentioning

confidence: 99%

3D bioprinting for cardiovascular regeneration and pharmacology

Cui

Miao

Esworthy

et al. 2018

Advanced Drug Delivery Reviews

148

116

View full text Add to dashboard Cite

Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide. Compared to traditional therapeutic strategies, three-dimensional (3D) bioprinting is one of the most advanced techniques for creating complicated cardiovascular implants with biomimetic features, which are capable of recapitulating both the native physiochemical and biomechanical characteristics of the cardiovascular system. The present review provides an overview of the cardiovascular system, as well as describes the principles of, and recent advances in, 3D bioprinting cardiovascular tissues and models. Moreover, this review will focus on the applications of 3D bioprinting technology in cardiovascular repair/regeneration and pharmacological modeling, further discussing current challenges and perspectives.

show abstract

“…[74] . Cardiac tissue engineering: Myocardial infarction is one of the death rate cause both in developing country and in developed country [75] . Myocardial tissue is conductive, whose main function is transmitting electrical signals to induce the heartbeat.…”

Section: Cell Deliverymentioning

confidence: 99%