3D printed microfluidic devices and applications

Phung, Sui Ching; Zhu, Qingfu; Plevniak, Kimberly; He, Mei

doi:10.1016/b978-0-12-819971-8.00007-x

Cited by 3 publications

(1 citation statement)

References 33 publications

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“…In 2002, Cooper first described the fabrication of microfluidic devices with PDMS using the solid-object printer, and this method gives the lowest resolution of 250 μm[ 22 ]. The low cost, time-saving, high precision of 3D structures, and surface finishing features of 3D printing were soon popularized in the field of microfluidic chips[ 23 ]. In addition, some commercial 3D printers with ultra-high resolution[ 24 ] (2 μm, nanoArch S130; BMF Precision Tech Inc., Chongqing, China) further narrowed the gap between 3D printing and the traditional soft lithography fabrication technique.…”

Section: Microfluidic Chipsmentioning

confidence: 99%

Advances in microfluidic chips based on islet hormone-sensing techniques

Li¹,

Peng²

2023

World J Diabetes

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Diabetes mellitus is a global health problem resulting from islet dysfunction or insulin resistance. The mechanisms of islet dysfunction are still under investigation. Islet hormone secretion is the main function of islets, and serves an important role in the homeostasis of blood glucose. Elucidating the detailed mechanism of islet hormone secretome distortion can provide clues for the treatment of diabetes. Therefore, it is crucial to develop accurate, real-time, labor-saving, high-throughput, automated, and cost-effective techniques for the sensing of islet secretome. Microfluidic chips, an elegant platform that combines biology, engineering, computer science, and biomaterials, have attracted tremendous interest from scientists in the field of diabetes worldwide. These tiny devices are miniatures of traditional experimental systems with more advantages of time-saving, reagent-minimization, automation, high-throughput, and online detection. These features of microfluidic chips meet the demands of islet secretome analysis and a variety of chips have been designed in the past 20 years. In this review, we present a brief introduction of microfluidic chips, and three microfluidic chips-based islet hormone sensing techniques. We focus mainly on the theory of these techniques, and provide detailed examples based on these theories with the hope of providing some insights into the design of future chips or whole detection systems.

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Section: Microfluidic Chipsmentioning

confidence: 99%

Advances in microfluidic chips based on islet hormone-sensing techniques

Li¹,

Peng²

2023

World J Diabetes

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Luminescent properties of metal–organic frameworks embedded in methacrylated gelatin for its application in biocompatible 3D printable materials

et al. 2022

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3D printing for ultra-precision machining: current status, opportunities, and future perspectives

He,

Yip,

Yan

et al. 2024

Front. Mech. Eng.

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Additive manufacturing, particularly 3D printing, has revolutionized the manufacturing industry by allowing the production of complex and intricate parts at a lower cost and with greater efficiency. However, 3D-printed parts frequently require post-processing or integration with other machining technologies to achieve the desired surface finish, accuracy, and mechanical properties. Ultra-precision machining (UPM) is a potential machining technology that addresses these challenges by enabling high surface quality, accuracy, and repeatability in 3D-printed components. This study provides an overview of the current state of UPM for 3D printing, including the current UPM and 3D printing stages, and the application of UPM to 3D printing. Following the presentation of current stage perspectives, this study presents a detailed discussion of the benefits of combining UPM with 3D printing and the opportunities for leveraging UPM on 3D printing or supporting each other. In particular, future opportunities focus on cutting tools manufactured via 3D printing for UPM, UPM of 3D-printed components for real-world applications, and post-machining of 3D-printed components. Finally, future prospects for integrating the two advanced manufacturing technologies into potential industries are discussed. This study concludes that UPM is a promising technology for 3D-printed components, exhibiting the potential to improve the functionality and performance of 3D-printed products in various applications. It also discusses how UPM and 3D printing can complement each other.

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3D printed microfluidic devices and applications

Cited by 3 publications

References 33 publications

Advances in microfluidic chips based on islet hormone-sensing techniques

Advances in microfluidic chips based on islet hormone-sensing techniques

Luminescent properties of metal–organic frameworks embedded in methacrylated gelatin for its application in biocompatible 3D printable materials

3D printing for ultra-precision machining: current status, opportunities, and future perspectives

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