3D Printed Multi-layer Molds of Human Head Tissue Phantoms for Microwave Stroke Detection

Pokorny, Tomas

doi:10.1109/piers-spring46901.2019.9017648

Cited by 5 publications

(2 citation statements)

References 6 publications

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“…To obtain realistic phantoms it is crucial to get as close to the anatomy by using Magnetic Resonance Imaging (MRI) or Computed Tomography (CT) scans to develop phantoms for imaging with MRI, CT, positron emission computed tomography (PET), single-photon emission computerized tomography (SPECT), and ultrasound [ 26 ]. In the microwave imaging domain, anthropomorphic head phantoms were developed by printing 3D molds intended to be filled with gel-based parts of the head [ 27 , 28 ] or mixtures based on graphite carbon black polyurethane [ 29 , 30 ]. A review of the development of anthropomorphic breast phantoms is given in [ 31 ].…”

Section: Methodsmentioning

confidence: 99%

A Simulation-Based Methodology of Developing 3D Printed Anthropomorphic Phantoms for Microwave Imaging Systems

et al. 2021

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This work is devoted to the development and manufacturing of realistic benchmark phantoms to evaluate the performance of microwave imaging devices. The 3D (3 dimensional) printed phantoms contain several cavities, designed to be filled with liquid solutions that mimic biological tissues in terms of complex permittivity over a wide frequency range. Numerical versions (stereolithography (STL) format files) of these phantoms were used to perform simulations to investigate experimental parameters. The purpose of this paper is two-fold. First, a general methodology for the development of a biological phantom is presented. Second, this approach is applied to the particular case of the experimental device developed by the Department of Electronics and Telecommunications at Politecnico di Torino (POLITO) that currently uses a homogeneous version of the head phantom considered in this paper. Numerical versions of the introduced inhomogeneous head phantoms were used to evaluate the effect of various parameters related to their development, such as the permittivity of the equivalent biological tissue, coupling medium, thickness and nature of the phantom walls, and number of compartments. To shed light on the effects of blood circulation on the recognition of a randomly shaped stroke, a numerical brain model including blood vessels was considered.

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Section: Methodsmentioning

confidence: 99%

A Simulation-Based Methodology of Developing 3D Printed Anthropomorphic Phantoms for Microwave Imaging Systems

et al. 2021

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“…MRI investigations are of great use in the development of molds design and CAD architecture, which help by offering predictions for future cases. Pokorni and Tesarik [ 146 ] developed molds from PET-G polymer to produce phantoms of the human head tissues (skin, bone, cerebrospinal fluid, brain), to mimic head geometry and evaluate stroke detection mechanisms that can be further applied to patients. The design of the molds was developed from MRI-derived scans.…”

Section: Applications That Use 3d-printed Polymeric Moldsmentioning

confidence: 99%

The Use of Additive Manufacturing Techniques in the Development of Polymeric Molds: A Review

Pelin,

Sonmez,

Pelin

2024

Polymers

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The continuous growth of additive manufacturing in worldwide industrial and research fields is driven by its main feature which allows the customization of items according to the customers’ requirements and limitations. There is an expanding competitiveness in the product development sector as well as applicative research that serves special-use domains. Besides the direct use of additive manufacturing in the production of final products, 3D printing is a viable solution that can help manufacturers and researchers produce their support tooling devices (such as molds and dies) more efficiently, in terms of design complexity and flexibility, timeframe, costs, and material consumption reduction as well as functionality and quality enhancements. The compatibility of the features of 3D printing of molds with the requirements of low-volume production and individual-use customized items development makes this class of techniques extremely attractive to a multitude of areas. This review paper presents a synthesis of the use of 3D-printed polymeric molds in the main applications where molds exhibit a major role, from industrially oriented ones (injection, casting, thermoforming, vacuum forming, composite fabrication) to research or single-use oriented ones (tissue engineering, biomedicine, soft lithography), with an emphasis on the benefits of using 3D-printed polymeric molds, compared to traditional tooling.

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Automated, Reproducible, and Reconfigurable Human Head Phantom for Experimental Testing of Microwave Systems for Stroke Classification

Pokorny,

Drizdal,

Novak

et al. 2024

Int J Imaging Syst Tech

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Microwave systems for prehospital stroke classification are currently being developed. In the future, these systems should enable rapid recognition of the type of stroke, shorten the time to start treatment, and thus significantly improve the prognosis of patients. In this study, we realized a realistic and reconfigurable 3D human head phantom for the development, testing, and validation of these newly developed diagnostic methods. The phantom enables automated and reproducible measurements for different positions of the stroke model. The stroke model itself is also interchangeable, so measurements can be made for different types, sizes, and shapes of strokes. Furthermore, an extensive series of measurements was performed at a frequency of 1 GHz, and an SVM classification algorithm was deployed, which successfully identified ischemic stroke in 80% of the corresponding measured data. If similar classification accuracy could be achieved in patients, it would lead to a dramatic reduction in the consequences of strokes.

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3D Printed Multi-layer Molds of Human Head Tissue Phantoms for Microwave Stroke Detection

Cited by 5 publications

References 6 publications

A Simulation-Based Methodology of Developing 3D Printed Anthropomorphic Phantoms for Microwave Imaging Systems

A Simulation-Based Methodology of Developing 3D Printed Anthropomorphic Phantoms for Microwave Imaging Systems

The Use of Additive Manufacturing Techniques in the Development of Polymeric Molds: A Review

Automated, Reproducible, and Reconfigurable Human Head Phantom for Experimental Testing of Microwave Systems for Stroke Classification

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