3D printing applications towards the required challenge of stem cells printing

Abstract

Background: Additive Manufacturing (AM) technologies are innovative and are being applied successfully in the medical field as they provide the extensive capability of customisation. Here in this study, we have identified research papers on AM applications, specifically 3D printing in stem cells. Aim of work:This study provides information to health professionals and helps them to solve different medical challenges in an effective manner which is not possible with the traditional method of stem cells fabrication. Materials and methods: Undertook the study through good research papers published on Stem cells on the applications of 3D printing which are also helpful to sort out different medical problems and their solution. Result: This paper studies 3D printing technology in the context of stem cells fabrications, brief about the stem cells, its functions and its superior capabilities in the medical field. Paper identified thirteen significant stem cells applications achievable through the practical applications of 3D printing. Finally, the paper provides a brief discussion on the future potential of this technology for the printing of stem cells. Conclusions: 3D printed stem cells seem to have extensive applications in regenerative medicine for the treatment of various diseases. These cells help seed decellularisation of complete organs for regenerative medicine. This technology also applies to the reconstruction of heart valves and has excellent potential in valvular disease. These cells have higher capabilities to fulfil different medical requirements, but it is challenging to steer its growth as per the need of human kind. Scientists created 3D printed stem cells structure which can grow, and they have performed tissue regeneration experiments on them. Traditionally researchers produce 2D sheets of cells. Now, this technology introduces the fabrications in 3D with stem cells which can also be developed in the human body. 3D printing approach creates uniform building blocks of stem cells with precise and controlled growth and seems helpful to the human body for consistent tissue growth. Nevertheless, this is just a starting, and there is a long way to go for commercial printing of human body parts.

A review on the role of 3D printing in the fight against COVID-19: safety and challenges

“…This section only discusses the future challenges of the application of 3D printing with regard to COVID-19 and a similar pandemic in the future. General challenges involving additive manufacturing and 3D printing are available in many works of literature including but not limited to Ngo et al (2018), Buchanan and Gardner (2019), Whyte et al (2019), Boer et al (2020), Das et al (2020), Javaid and Haleem (2020), Shahrubudin et al (2020).…”

3D-printed microneedles in biomedical applications

“…Each 3D printing method has a unique set of tradeoffs in resolution, cost-efficiency, biocompatibility, and output volume, enabling the use of 3D printing in a wide range of applications ( Bakhshinejad and D'souza, 2015 ; Park et al., 2015 ). The ability to use biomaterials in 3D printing processes ( Chia and Wu, 2015 ), along with microscale and nanoscale 3D printing ( You et al., 2018 ), can enable the fabrication of a wide range of laboratory instruments for clinical and point-of-care applications ( Aimar et al., 2019 ; Amin et al., 2016b ; Douroumis, 2019 ; Knowlton et al., 2015c ; Yenilmez et al., 2016a ), including organ-on-a-chip devices ( Jain et al., 2020 ; Knowlton and Tasoglu, 2016 ; Knowlton et al., 2016b , 2016c ), tissue engineering ( Knowlton et al., 2018 ; Sears et al., 2016 ; Zhang et al., 2019 ), wound healing ( Joseph et al., 2019 ; Tabriz et al., 2020 ), fertility and embryology research ( Kanakasabapathy et al., 2019 ; Knowlton et al., 2015d ; Potluri et al., 2018 ), cancer research ( Knowlton et al., 2015a , 2016a ), stem cell research ( Javaid and Haleem, 2020 ; Tasoglu and Demirci, 2013 ), and circulating tumor cell isolation ( Chen et al., 2020 ).…”

A 3D Printer Guide for the Development and Application of Electrochemical Cells and Devices

“…In this context, the emerging technology of 3D printing has stood out in the last decade and has promised to revolutionize the production in several sectors, such as R&D, aerospace, industry, diagnostics, healthcare, dentistry, engineering, civil construction, education, food, arts, among others. (Huang et al, 2013;Kanada, 2014;Siebert and Teizer, 2014;Wong and Pfahnl, 2014;Gupta et al, 2015;Micallef, 2015;Pallottino et al, 2016;Iyer et al, 2017;Derossi et al, 2018;Hamilton et al, 2018;Jones and Spencer, 2018;Prakash et al, 2018;Javaid and Haleem, 2020;Zhu et al, 2021) 3D printing is defined as an additive manufacturing (AM) technology created to build three-dimensional objects. Accordingly, AM is a process that produces 3D objects (hollow or filled) by the deposit of the raw material layers by layers.…”