3D printing of PLA:CaP:GO scaffolds for bone tissue applications

Abstract

PLA:CaP:GO scaffolds were fabricated with a previously optimised biocompatible dose of GO and then characterised physicochemically and in a zebrafish model.

Evaluation of the dispersion properties of graphene oxide/cetyltrimethylammonium bromide for application in nanocomposite materials

“…These scaffolds, with controlled degradation over time, offer a promising solution for enhancing bone regeneration procedures in tissue engineering and regenerative medicine. 11…”

“…6,8,9 In this context, poly(lactic acid) (PLA) is a biodegradable synthetic polymer, which is also important for biomedical applications, however, it has some limitations such as its low thermal and electrical properties, low impact resistance, and brittleness. 10 Therefore, the use of llers nanomaterials such as G, GO, and rGO is an important line of research focused on improving the properties of PLA 11 and of different types of polymeric matrix. [12][13][14] PLA/GO is being used in biomedical applications related to bone tissue engineering and obtaining techniques such as 3D printing, 15 where the porosity and geometry of the scaffolds are precisely controlled to facilitate union, growth, differentiation cellular formation and the formation of new bone tissue.…”