2024
DOI: 10.1002/mabi.202400088
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3D Puzzle at the Nanoscale–How do RNA Viruses Self‐Assemble their Capsids into Perfectly Ordered Structures

Martyna Kordys,
Anna Urbanowicz

Abstract: The phenomenon of RNA virus self‐organization, first observed in the mid‐20th century in tobacco mosaic virus, is the subject of extensive research. Efforts to comprehend this process intensify due to its potential for producing vaccines or antiviral compounds as well as nanocarriers and nanotemplates. However, direct observation of the self‐assembly is hindered by its prevalence within infected host cells. One of the approaches involves in vitro and in silico research using model viruses featuring a ssRNA(+) … Show more

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