3D-QSAR-based design, synthesis and biological evaluation of 2,4-disubstituted quinoline derivatives as antimalarial agents

Biannual Account of Anti‐malarial Agents reported in 2021 and 2022: A Comprehensive Coverage

“…In our previous work, we have provided the coverage of medicinal aspects of heterocycles as anti-malarial scaffolds published during 2016-2020. [29] In continuation to the ongoing efforts on the synthesis of heterocycles [30][31][32][33][34][35][36] as medicinally important scaffolds [37,38] or anti-malarial agents, [39][40][41][42] the present work provides the detail aspects of all the reported heterocycles reported in 2021 and 2022 for the interest of medicinal chemists working on anti-malarial drug development along with their pharmacophoric features, structure-activity relationships (SAR), potential against multi-drug resistant strains, mode of actions, in silico/ in vitro/ in vivo activity, if reported.…”