4-[(2,5-Dimethyl-1,3-thiazol-4-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione

Abstract

In the title isoquinoline­dione compound, C16H16N2O3S, the piperidine ring in the tetra­hydro­isoquinoline ring system adopts a half-boat conformation. The essentially planar thia­zole ring [maximum deviation = 0.007 (2) Å] makes a dihedral angle of 34.49 (7)° with the mean plane through the tetra­hydro­isoquinoline ring system. In the crystal structure, two neighbouring mol­ecules are linked via pairs of O—H⋯N and C—H⋯O hydrogen bonds into inversion-related dimers incorporating R 2 2(9) hydrogen-bond ring motifs. These dimers are further linked by weak inter­molecular C—H⋯π inter­actions.