4-(3-Hydroxy-4-methoxyphenyl)-3-(3,4,5-trimethoxyphenyl)-2,5-dihydro-1H-pyrrole-2,5-dione

Abstract

Key indicatorsSingle-crystal X-ray study T = 295 K Mean (C-C) = 0.005 Å R factor = 0.051 wR factor = 0.145 Data-to-parameter ratio = 7.4For details of how these key indicators were automatically derived from the article, see

Design, Synthesis, and Biological Evaluation of 3,4-Diarylmaleimides as Angiogenesis Inhibitors

“…X-ray analysis: CAD4 Enraf Nonius, Cu Kα, SIR-92, SHELXL-97. Further details of the crystal structure analysis are available in ref .…”

The Solid-State Structures of Cyclic NH Carboximides

“…It would seem that the presence of smaller substituents favours this structure whereas larger substituents more commonly lead to the dimeric pattern A. Three structures, 21, 22 [26] and 23 [27] (Figure 7) show a linear chain where the NH of the imides is hydrogen-bonded to a remote ester or ether oxygen (pattern F or C (8)). In the case of compound 23 there is an additional C (11) interaction between the phenolic OH and a further ether oxygen leading to cross-linking of the chains.…”

“…Compound 24 [28] forms a linear chain with the imide NH bonded to the remote pyridine nitrogen (pattern E or C (9)) and additionally, an intramolecular (S(6)) hydrogen bond between the 2-NH on the pyridyl ring and the amide oxygen. Three structures, 21, 22 [26] and 23 [27] (Figure 7) show a linear chain where the NH of the imides is hydrogen-bonded to a remote ester or ether oxygen (pattern F or C(8)). In the case of compound 23 there is an additional C (11) interaction between the phenolic OH and a further ether oxygen leading to cross-linking of the chains.…”