4,4′-Bis[4-(4′-hydroxyphenyl)phenylazo]diphenyl Ether

Rahman, Rahima; Gul, Asghari; Akhter, Zareen

doi:10.3390/m914

Cited by 2 publications

(1 citation statement)

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“…Substituted azobenzene have attracted considerable attention based on their various physical and chemical properties, such as bright colors, good stability, low flammability, and rapid, reversible photo-isomerization [1][2][3][4] . Aromatic azo compounds are widely used in the chemical industry as dyes, pigments 5,6 , food additives 7, indicators 3 , radical reaction initiators 8 and therapeutic agents 9,10 .…”

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization and in vitro biological screening of 4-hydroxy naphthalen-1-yl, naphtho[1,2-b]furan, benzo[h]chromene and 5,6-dihydropyridazine derivatives containing sulfonamide moiety

et al. 2018

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In this study, a series of 4-((4-hydroxynaphthalen-1-yl)diazenyl)benzenesulfonamides have been prepared by subsequent diazotization of sulfonamide derivatives and coupling with 1-naphthol in alkaline medium. Cyclization of 4-((4-hydroxynaphthalen-1-yl)diazenyl)benzenesulfonamides with cinnamic acid in the presence of a basic catalyst afforded the novel naphtho[1,2-b]furans. Also, 4-((4-hydroxynaphthalen-1-yl)diazenyl)benzenesulfonamides can be cyclized with α‐cyanocinnamonitriles to afford 2-amino-3-cyano-4-phenyl-4H-benzo[h]chromenes. 4-(4-amino-3,5- dicyano-6-iminopyridazin-1(6H)-yl)benzenesulfonamides were obtained at room temperature by treatment of 2-amino-1,1,3-tricyanopropene with a diazonium salt of sulfonamide derivatives. The structures of newly synthesized compounds were confirmed by analytical data and spectroscopic techniques. The antimicrobial activity of the obtained compounds was assessed in vitro by qualitative and quantitative (minimum inhibitory concentration) (MIC) assays.

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