“…Water (200 ml) was then added and the solid hydroxyamide that precipitated was collected and dried (0.83 g, 92% yield), mpt 114-5 • C. FT-IR (neat) 3314, 1683, 1671, 1468, 1450, 1421, 1044, 751, 704, 695 cm -1 . 1 H NMR (500 MHz, CDCl 3 ): d = 1.51-1.70 (4H, m), 2.61 (2H, t, J = 5.8 Hz), 3.20-3.28 (1H, m), 3.39-3.48 (1H, m), 3.56 (1H, d, J = 11.9 Hz), 5.67 (1H, d, J = 11.9 Hz), 7.11-7.17 (3H, m), 7.24 (2H, t, J = 7.5 Hz), 7.42 (1H, dt, J = 0.95, 7.4 Hz), 7.52-7.60 (3H, m); 13 A solution of the hydroxyamide (0.44 g, 1.5 mmol) in CHCl 3 (5 ml) was added to a stirred mixture of triflic acid (1.5 ml) in CHCl 3 (20 ml) and the reaction mixture heated under reflux for 2 h. On cooling, water was added (10 ml) and the aqueous layer made basic by careful addition of solid K 2 CO 3 . The product was extracted into DCM (3 ¥ 50 ml), dried (K 2 CO 3 ), concentrated and purified by column chromatography on SiO 2 , eluting with 1 : 1 petrol : DCM to give the title compound 6 as a white solid (0.30 g, 73% yield), mpt 150-152…”