4′-(4-Chlorophenyl)-3′-(4-methoxyphenyl)-3,4-dihydro-1H,4′H-spiro[acridine-2,5′-isoxazol]-1-one

Abstract

Key indicators: single-crystal X-ray study; T = 293 K; mean (C-C) = 0.003 Å; R factor = 0.037; wR factor = 0.108; data-to-parameter ratio = 13.9.In the title compound, C 28 H 21 ClN 2 O 3 , the quinoline ring system is essentially planar with a maximum deviation of 0.0436 (17) Å . The isoxazole and cyclohexane rings adopt envelope conformations. The isoxazole ring is almost orthogonal to both the quinoline ring system and the cyclohexane ring, making dihedral angles of 85.75 (8) and 81.46 (9) , respectively. The O atom deviates signifigantly from the sixmembered carbocyclic ring by 0.3947 (16) Å . In the crystal, molecules are linked into inversion dimers via pairs of C-HÁ Á ÁO interactions, resulting in R 2 2 (24) ring motifs.