4‐Anilinoquinazolines with Lavendustin A Subunit as Inhibitors of Epidermal Growth Factor Receptor Tyrosine Kinase: Syntheses, Chemical and Pharmacological Properties.

Abstract

Fused pyrimidine derivatives R 0515 4-Anilinoquinazolines with Lavendustin A Subunit as Inhibitors of EpidermalGrowth Factor Receptor Tyrosine Kinase: Syntheses, Chemical and Pharmacological Properties. -4-Anilinoquinazolines (V) demonstrate moderate inhibition of epidermal growth factor receptor tyrosine kinase and cause antiproliferative to cytotoxic effects on certain human cancer cell lines. -(ALBUSCHAT, R.; LOEWE*, W.; WEBER, M.; LUGER, P.; JENDROSSEK, V.; Eur.