4-Phenyl-6,7,8,9-tetrahydro-1H-2,3-benzodiazepine 2-oxide, C15H16N2O

Abstract

(2) and 1.268 (2) A respectively. The boat conformation adopted by most 1,2-diazepine rings is unperturbed by the oxide ligand which serves to weaken the N=N double bond and lowers the activation energy for ring inversion.

Thionordazepam: strong intermolecular N—H...N hydrogen-bonded chains

“…The central seven-membered diazepinthione ring (atoms C4/C5/C7-C9/N1/N2) adopts a boat conformation. The boat conformation is predominantly observed for the seven-membered ring of benzodiazepine and its derivatives, even with different double-bond positions and widely differing substituents (Walkinshaw, 1985;Torres et al, 2005). The internal torsion angles of the ring are shown in Fig.…”