2023
DOI: 10.26434/chemrxiv-2023-l3lhp
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4-Pyridyl perfluoroalkyl sulfide as a practical nucleophilic perfluoroalkylation reagent

Fei-Yu Zhou,
Lei Jiao

Abstract: The incorporation of perfluoroalkyl groups into molecules leads to unique properties, and perfluoroalkylation reagents play a vital role in facilitating this process. Although various types of perfluoroalkylation reagents have been developed, the established nucleophilic perfluoroalkylation reagents have faced certain limitations. This work aims to address these challenges by introducing a novel nucleophilic perfluoroalkylation reagent, known as 4-pyridyl perfluoroalkyl sulfide (4-PySRf), which demonstrates a … Show more

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